S-Glycidyl Acetate

Base Information

• Chemical Name: S-Glycidyl Acetate
• CAS No.: 65031-95-0
• Molecular Formula: C5H8O3
• Molecular Weight: 116.117
• Hs Code.: 2915390090
• Mol file: 65031-95-0.mol

Synonyms:Oxiranemethanol,acetate, (2S)- (9CI);Oxiranemethanol, acetate, (S)-;

Chemical Property of S-Glycidyl Acetate

Chemical Property:

• Vapor Pressure: 4.59mmHg at 25°C
• Refractive Index: 1.434
• Boiling Point: 146.7 °C at 760 mmHg
• Flash Point: 69.6 °C
• PSA: 38.83000
• Density: 1.14 g/cm³
• LogP: -0.05170

Purity/Quality:

98%Min ^*data from raw suppliers

(S)-GLYCIDYL ACETATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of S-Glycidyl Acetate

There total 3 articles about S-Glycidyl Acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

vinyl acetate (108-05-4,9003-20-7) + oxiranyl-methanol (556-52-5) → (2S)-oxiran-2-ylmethyl acetate (65031-95-0) + (R)-oxiranemethanol (57044-25-4)

Guidance literature:

Lipase P; In dichloromethane; Ambient temperature;

DOI:10.1016/S0040-4039(00)61533-2

Reference yield:

Isopropenyl acetate (108-22-5) + oxiranyl-methanol (556-52-5) → (2R)-oxiran-2-ylmethyl acetate + (2S)-oxiran-2-ylmethyl acetate (65031-95-0)

Guidance literature:

With Candida antarctica lipase B imobilized on epoxi 8214; In tert-butyl methyl ether; at 20 ℃; Reagent/catalyst; Optical yield = 58 %ee; Resolution of racemate; Enzymatic reaction;

DOI:10.1002/ejoc.201800345

Reference yield:

vinyl acetate (108-05-4,9003-20-7) + (S)-oxiranemethanol (60456-23-7) → (2S)-oxiran-2-ylmethyl acetate (65031-95-0)

Guidance literature:

Lipase P; In dichloromethane; Ambient temperature;

DOI:10.1016/S0040-4039(00)61533-2

upstream raw materials:

vinyl acetate

oxiranyl-methanol

(S)-oxiranemethanol

Isopropenyl acetate

Refernces

• 1、 Chen, Jian. "A direct HPLC method for the determination of enantiomeric excess of some highly enantiomerically enriched derivatives of chiral glycidols". . p. 7663 - 7666. Retrieved 2007/10/02.