5-Methoxy-N-methyl-N-isopropyltryptamine

Base Information

• Chemical Name: 5-Methoxy-N-methyl-N-isopropyltryptamine
• CAS No.: 96096-55-8
• Molecular Formula: C₁₅H₂₂N₂O
• Molecular Weight: 246.352
• Hs Code.: 2933990090
• European Community (EC) Number: 695-060-3
• UNII: L0P1807EUY
• DSSTox Substance ID: DTXSID90242114
• Nikkaji Number: J397.911C
• Wikipedia: 5-MeO-MiPT
• Wikidata: Q4412834
• ChEMBL ID: CHEMBL172139
• Mol file: 96096-55-8.mol

Synonyms:5-MeO-MIPT;5-methoxy-N-methyl,N-isopropyl tryptamine

 This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of 5-Methoxy-N-methyl-N-isopropyltryptamine

Chemical Property:

• Appearance/Colour: White powder
• Vapor Pressure: 2.67E-06mmHg at 25°C
• Refractive Index: 1.576
• Boiling Point: 390.3 °C at 760 mmHg
• PKA: 17.09±0.30(Predicted)
• Flash Point: 189.9 °C
• PSA: 28.26000
• Density: 1.06 g/cm³
• LogP: 3.05920
• Storage Temp.: -20°C
• Solubility.: Chloroform (Slightly), Methanol (Slightly)
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 246.173213330
• Heavy Atom Count: 18
• Complexity: 257

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)N(C)CCC1=CNC2=C1C=C(C=C2)OC
• Uses: 5-Methoxy MiPT is a psychedelic tryptamine related to N-methyl-N-isopropyltryptamine. 5-Methoxy MiPT potently inhibits the re-uptake of the monoamines serotonin and norepinephrine but does not affect dopamine re-uptake. 5-Methoxy MiPT has no effect on the release of monoamines from rat brain synaptosomes. This product is intended for forensic and research applications.

Technology Process of 5-Methoxy-N-methyl-N-isopropyltryptamine

There total 5 articles about 5-Methoxy-N-methyl-N-isopropyltryptamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-methoxy-N-methyltryptamine (2009-03-2) + acetone (67-64-1) → 5-methoxy-N-methyl-N-isopropyltryptamine (96096-55-8)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; for 15h; under 2585.7 Torr; Yield given;

DOI:10.1021/jm00145a007

Reference yield:

5-methoxylindole (1006-94-6) → 5-methoxy-N-methyl-N-isopropyltryptamine (96096-55-8)

Guidance literature:

Multi-step reaction with 5 steps

1: 85 percent / tert-butylcatechol / xylene / 3 h / Heating

2: H₂ / 10 percent Pd/C / ethanol / 12 h / 2585.7 Torr

3: K₂CO₃ / H₂O; toluene / 15 h / Ambient temperature

4: lithium aluminum hydride / tetrahydrofuran / 0.5 h / Heating

5: H₂ / 10 percent Pd/C / ethanol / 15 h / 2585.7 Torr

With lithium aluminium tetrahydride; 3-tert-butylbenzene-1,2-diol; hydrogen; potassium carbonate; palladium on activated charcoal; In tetrahydrofuran; ethanol; water; toluene; xylene;

DOI:10.1021/jm00145a007

Reference yield:

2-(5-methoxyindol-3-yl)ethylamine (608-07-1) → 5-methoxy-N-methyl-N-isopropyltryptamine (96096-55-8)

Guidance literature:

Multi-step reaction with 3 steps

1: K₂CO₃ / H₂O; toluene / 15 h / Ambient temperature

2: lithium aluminum hydride / tetrahydrofuran / 0.5 h / Heating

3: H₂ / 10 percent Pd/C / ethanol / 15 h / 2585.7 Torr

With lithium aluminium tetrahydride; hydrogen; potassium carbonate; palladium on activated charcoal; In tetrahydrofuran; ethanol; water; toluene;

DOI:10.1021/jm00145a007

upstream raw materials:

5-methoxy-N-methyltryptamine

acetone

5-methoxylindole

2-(5-methoxyindol-3-yl)ethylamine

Refernces