(3-TRIFLUOROMETHOXY-PHENYL)-HYDRAZINE HYDROCHLORIDE

Base Information

• Chemical Name: (3-TRIFLUOROMETHOXY-PHENYL)-HYDRAZINE HYDROCHLORIDE
• CAS No.: 133115-55-6
• Molecular Formula: C₇H₇F₃N₂O*ClH
• Molecular Weight: 228.602
• Hs Code.: 29280000
• Mol file: 133115-55-6.mol

Synonyms:Hydrazine,[3-(trifluoromethoxy)phenyl]-, monohydrochloride (9CI);

Chemical Property of (3-TRIFLUOROMETHOXY-PHENYL)-HYDRAZINE HYDROCHLORIDE

Chemical Property:

• Vapor Pressure: 0.0803mmHg at 25°C
• Refractive Index: 1.526
• Boiling Point: 226.8oC at 760 mmHg
• Flash Point: 91oC
• PSA: 47.28000
• Density: 1.408g/cm3
• LogP: 3.44610
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

(3-(Trifluoromethoxy)phenyl)hydrazinehydrochloride ^*data from reagent suppliers

Safty Information:

• Statements: 20/21/22-36/37/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (3-TRIFLUOROMETHOXY-PHENYL)-HYDRAZINE HYDROCHLORIDE

There total 4 articles about (3-TRIFLUOROMETHOXY-PHENYL)-HYDRAZINE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

m-trifluoromethoxyaniline (1535-73-5) → [3-(trifluoromethoxy)phenyl]hydrazine hydrochloride (133115-55-6)

Guidance literature:

m-trifluoromethoxyaniline; With hydrogenchloride; sodium nitrite; In water; at -5 ℃; for 0.333333h;

With hydrogenchloride; tin(ll) chloride; In water; at -5 ℃; for 2h;

Reference yield:

m-trifluoromethoxyaniline (1535-73-5) → [3-(trifluoromethoxy)phenyl]hydrazine hydrochloride (133115-55-6)

Guidance literature:

With hydrogenchloride; tin(ll) chloride; sodium nitrite; In water; at -5 ℃; for 2h;

Reference yield:

tin(II)chloride dihydrate + m-trifluoromethoxyaniline (1535-73-5) → [3-(trifluoromethoxy)phenyl]hydrazine hydrochloride (133115-55-6)

Guidance literature:

With sodium hydroxide; urea; sodium nitrite; In hydrogenchloride; water;

upstream raw materials:

m-trifluoromethoxyaniline

Downstream raw materials:

1-[2-fluoro-4-(1H-pyrazol-1-yl)phenyl]-5-methoxy-3-{1-[3-(trifluoromethoxy)phenyl]-1H-pyrazol-5-yl}pyridazin-4(1H)-one

Refernces

• 1、 -. "HETEROCYCLIC COMPOUND". Paragraph 0480; 0481. . Retrieved 2013/06/27.
• 2、 -. "Trifluoromethoxy substituted 1,3,4,9-tetrahydropyrano-[3,4-b]indole-1-acetic acids". . . Retrieved 2008/06/13.