phenyl 2-iodopropionate

Base Information

• Chemical Name: phenyl 2-iodopropionate
• CAS No.: 251346-05-1
• Molecular Formula: C₉H₉IO₂
• Molecular Weight: 276.074
• Mol file: 251346-05-1.mol

Synonyms:phenyl 2-iodopropionate

Chemical Property of phenyl 2-iodopropionate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of phenyl 2-iodopropionate

There total 2 articles about phenyl 2-iodopropionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

phenyl 2-bromopropionate (42710-26-9) → phenyl 2-iodopropionate (251346-05-1)

Guidance literature:

With potassium iodide; In acetone; Heating;

DOI:10.1021/ol990971n

Reference yield:

phenol (108-95-2,27073-41-2) → phenyl 2-iodopropionate (251346-05-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 84 percent / DCC; DMAP / diethyl ether / 1.5 h / 20 °C

2: 94 percent / KI / acetone / Heating

With dmap; dicyclohexyl-carbodiimide; potassium iodide; In diethyl ether; acetone;

DOI:10.1021/ol990971n

Reference yield: 82.0%

phenyl 2-iodopropionate (251346-05-1) → phenyl 2-hydroxypropionate (7292-85-5)

Guidance literature:

phenyl 2-iodopropionate; With triethyl borane; oxygen; In dichloromethane; 1,2-dichloro-ethane; at -50 ℃; for 5h;

With methanol; dimethylsulfide; In dichloromethane; 1,2-dichloro-ethane; at -50 ℃; for 0.25h; Further stages.;

DOI:10.1021/ol990971n

upstream raw materials:

phenyl 2-bromopropionate

phenol

Downstream raw materials:

phenyl 2-hydroxypropionate

Refernces