(4-PROPOXY-3-METHYL)BENZENEBORONIC ACID

Base Information

• Chemical Name: (4-PROPOXY-3-METHYL)BENZENEBORONIC ACID
• CAS No.: 279262-88-3
• Molecular Formula: C10H15BO3
• Molecular Weight: 194.038
• Hs Code.: 2931900090
• Mol file: 279262-88-3.mol

Synonyms:Boronicacid, (3-methyl-4-propoxyphenyl)- (9CI);3-Methyl-4-propoxyphenylboronic acid;(3-methyl-4-propoxyphenyl)boronic acid;3-Methyl-4-propoxybenzeneboronic acid;

Chemical Property of (4-PROPOXY-3-METHYL)BENZENEBORONIC ACID

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 154-156
• Refractive Index: 1.512
• Boiling Point: 345.492 °C at 760 mmHg
• PKA: 8.76±0.17(Predicted)
• Flash Point: 162.748 °C
• PSA: 49.69000
• Density: 1.088 g/cm³
• LogP: 0.46360
• Storage Temp.: Keep Cold

Purity/Quality:

99.99%HPLC ^*data from raw suppliers

4-Propoxy-3-methylphenylboronicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (4-PROPOXY-3-METHYL)BENZENEBORONIC ACID

There total 1 articles about (4-PROPOXY-3-METHYL)BENZENEBORONIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

Triisopropyl borate (5419-55-6) → 3-Methyl-4-propoxyphenyl boronic acid (279262-88-3)

Guidance literature:

(4-bromo-2-methyl-phenyl)-propyl ether; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 0.333333h;

Triisopropyl borate; In tetrahydrofuran; at -78 - 20 ℃; for 18.25h;

With hydrogenchloride; water;

Reference yield:

(2,4-dibromo-thiophen-3-yl)-acetic acid methyl ester (905838-65-5) + 3-Methyl-4-propoxyphenyl boronic acid (279262-88-3) → C17H19BrO3S

Guidance literature:

With potassium carbonate; palladium bis[bis(diphenylphosphino)ferrocene] dichloride; In 1,4-dioxane; at 45 ℃;

DOI:10.1016/j.bmcl.2007.08.010

upstream raw materials:

Triisopropyl borate

Refernces