2-Morpholin-4-yl-2-phenylethylamine

Base Information

• Chemical Name: 2-Morpholin-4-yl-2-phenylethylamine
• CAS No.: 31466-44-1
• Molecular Formula: C12H18N2O
• Molecular Weight: 206.28
• Hs Code.: 2934999090
• DSSTox Substance ID: DTXSID10390161
• Mol file: 31466-44-1.mol

Synonyms:31466-44-1;2-Morpholin-4-yl-2-phenylethylamine;2-Morpholin-4-yl-2-phenyl-ethylamine;2-morpholin-4-yl-2-phenylethanamine;2-Morpholino-2-phenylethanamine;2-(Morpholin-4-Yl)-2-Phenylethan-1-Amine;2-(morpholin-4-yl)-2-phenylethanamine;TimTec1_008424;SCHEMBL856294;DTXSID10390161;WSNSRJWLIVDXDI-UHFFFAOYSA-N;HMS1557O20;2-Morpholino-2-phenylethan-1-amine;2-Morpholin4-yl-2-phenyl-ethylamine;AR3497;BBL040585;MFCD01631944;STK350731;AKOS000153138;AKOS016040424;2-(Morpholin-4-yl)-2-phenylethylamine;NCGC00374337-01;BS-14019;[2-(Morpholin-4-yl)-2-phenylethyl]amine;BB 0218531;CS-0171277;FT-0678370;EN300-30489;A875900;Z285151724

Chemical Property of 2-Morpholin-4-yl-2-phenylethylamine

Chemical Property:

• Vapor Pressure: 0.000485mmHg at 25°C
• Refractive Index: 1.562
• Boiling Point: 313.8 °C at 760 mmHg
• PKA: 9.19±0.10(Predicted)
• Flash Point: 143.6 °C
• PSA: 38.49000
• Density: 1.098 g/cm³
• LogP: 1.65680
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 206.141913202
• Heavy Atom Count: 15
• Complexity: 175

Purity/Quality:

98%min ^*data from raw suppliers

2-Morpholin-4-yl-2-phenylethanamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1COCCN1C(CN)C2=CC=CC=C2

Technology Process of 2-Morpholin-4-yl-2-phenylethylamine

There total 5 articles about 2-Morpholin-4-yl-2-phenylethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

(2-morpholino-2-phenylethyl)carbamic acid tert-butyl ester → 2-(morpholin-4-yl)-2-phenylethan-1-amine (31466-44-1)

Guidance literature:

(2-morpholino-2-phenylethyl)carbamic acid tert-butyl ester; With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 1h;

With sodium hydroxide; In dichloromethane; water;

Reference yield:

morpholin-4-yl-phenyl-acetonitrile (15190-10-0) → 2-(morpholin-4-yl)-2-phenylethan-1-amine (31466-44-1)

Guidance literature:

With sodium;

DOI:10.1021/ja01162a600

Reference yield:

benzaldehyde (100-52-7) → 2-(morpholin-4-yl)-2-phenylethan-1-amine (31466-44-1)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂O

2: sodium

With water; sodium;

DOI:10.1021/ja01162a600

upstream raw materials:

morpholin-4-yl-phenyl-acetonitrile

2-morpholin-4-yl-2-phenyl-acetamide

benzaldehyde

Refernces