9-(oxiran-2-ylmethyl)-9H-carbazole

Base Information

• Chemical Name: 9-(oxiran-2-ylmethyl)-9H-carbazole
• CAS No.: 52131-82-5
• Molecular Formula: C₁₅H₁₃NO
• Molecular Weight: 223.274
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID70379573
• Nikkaji Number: J228.089B
• Mol file: 52131-82-5.mol

Synonyms:9-(oxiran-2-ylmethyl)-9H-carbazole;52131-82-5;9-(oxiran-2-ylmethyl)carbazole;9-Glycidyl-9H-carbazole;SCHEMBL409180;9-(2,3-epoxypropyl)carbazole;DTXSID70379573;VAJIZAPXBKMPRO-UHFFFAOYSA-N;9-(2-oxiranylmethyl)-9H-carbazole;BBL011731;MFCD00218388;STK387531;AKOS000200971;AKOS016042448;AS-9915;CS-0116685;FT-0621583;EN300-29535;10.14272/VAJIZAPXBKMPRO-UHFFFAOYSA-N;9-[(OXIRAN-2-YL)METHYL]-9H-CARBAZOLE;A828943;doi:10.14272/VAJIZAPXBKMPRO-UHFFFAOYSA-N;SR-01000321795;SR-01000321795-1;Z235363123;9-(Oxiran-2-ylmethyl)-9H-carbazole;InChI=1/C15H13NO/c1-3-7-14-12(5-1)13-6-2-4-8-15(13)16(14)9-11-10-17-11/h1-8,11H,9-10H2

Chemical Property of 9-(oxiran-2-ylmethyl)-9H-carbazole

Chemical Property:

• Vapor Pressure: 6.36E-07mmHg at 25°C
• Melting Point: 110oC
• Boiling Point: 409.7oC at 760 mmHg
• Flash Point: 201.6oC
• PSA: 17.46000
• Density: 1.25g/cm3
• LogP: 3.19330
• XLogP3: 3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 223.099714038
• Heavy Atom Count: 17
• Complexity: 271

Purity/Quality:

99%, ^*data from raw suppliers

9-(Oxiran-2-ylmethyl)-9H-carbazole ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1C(O1)CN2C3=CC=CC=C3C4=CC=CC=C42

Technology Process of 9-(oxiran-2-ylmethyl)-9H-carbazole

There total 6 articles about 9-(oxiran-2-ylmethyl)-9H-carbazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

9H-carbazole (86-74-8,105184-46-1,97960-57-1) + epichlorohydrin (106-89-8,24969-06-0,13403-37-7) → 9-(oxiran-2-ylmethyl)-9H-carbazole (52131-82-5,150447-51-1)

Guidance literature:

With potassium hydroxide; tetrabutylammomium bromide; potassium carbonate; In toluene; at 105 - 106 ℃; for 0.166667h; microwave irradiation;

DOI:10.1080/00397910500278479

Reference yield: 76.9%

9H-carbazole (86-74-8,105184-46-1,97960-57-1) + 1,2-Epoxy-3-bromopropane (3132-64-7,82584-73-4) → 9-(oxiran-2-ylmethyl)-9H-carbazole (52131-82-5,150447-51-1)

Guidance literature:

9H-carbazole; With potassium hydroxide; In N,N-dimethyl-formamide; for 0.5h; Cooling with ice;

1,2-Epoxy-3-bromopropane; In N,N-dimethyl-formamide; for 5h; Cooling with ice;

Reference yield: 70.0%

→ 9-(oxiran-2-ylmethyl)-9H-carbazole (52131-82-5,150447-51-1)

Guidance literature:

With potassium hydroxide; In N,N-dimethyl-formamide; Cooling with ice;

In N,N-dimethyl-formamide; Cooling with ice;

upstream raw materials:

potassium carbazole

epichlorohydrin

9-allyl-9H-carbazole

9H-carbazole

Downstream raw materials:

SJ000550851-1

Incentrom A

SJ000133382-2

Refernces

• 1、 -. "Carbazole isopropanol diamine compound containing 1, 2, 3-triazole as well as preparation method and application of carbazole isopropanol diamine compound". Paragraph 0047; 0048; 0051. . Retrieved 2021/04/03.
• 2、 -. "With chiral center carbazolyl isopropanolamine derivatives of the preparation method and application of (by machine translation)". Paragraph 0056; 0057; 0062; 0067. . Retrieved 2019/05/04.