(2,3-dimethoxyphenyl)propyl ketone

Base Information

• Chemical Name: (2,3-dimethoxyphenyl)propyl ketone
• CAS No.: 34052-09-0
• Molecular Formula: C₁₂H₁₆O₃
• Molecular Weight: 208.257
• Mol file: 34052-09-0.mol

Synonyms:(2,3-dimethoxyphenyl)propyl ketone

Chemical Property of (2,3-dimethoxyphenyl)propyl ketone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2,3-dimethoxyphenyl)propyl ketone

There total 5 articles about (2,3-dimethoxyphenyl)propyl ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(2,3-dimethoxyphenyl)-1-butanol (100520-92-1) → (2,3-dimethoxyphenyl)propyl ketone (34052-09-0)

Guidance literature:

With potassium dichromate; sulfuric acid;

DOI:10.1021/jo01105a606

Reference yield:

2,3-dimethyoxybenzaldehyde (86-51-1) → (2,3-dimethoxyphenyl)propyl ketone (34052-09-0)

Guidance literature:

Multi-step reaction with 2 steps

1.1: Mg / diethyl ether / 0.5 h / Heating

1.2: diethyl ether / 2 h / Heating

2.1: 0.9 g / Na₂Cr₂O₇; aq. H₂SO₄ / acetone / 3 h / 20 °C

With sodium dichromate; sulfuric acid; magnesium; In diethyl ether; acetone; 2.1: Jones oxidation;

DOI:10.1021/ja052326j

Reference yield:

2,3-dimethoxybenzoic acid (1521-38-6) → (2,3-dimethoxyphenyl)propyl ketone (34052-09-0)

Guidance literature:

Multi-step reaction with 2 steps

1: SOCl₂ / Heating

2: (i) Mg, Et₂O, (ii) CdCl₂, (iii) /BRN= 779052/

With thionyl chloride;

DOI:10.1021/jm00290a016

upstream raw materials:

1-(2,3-dimethoxyphenyl)-1-butanol

dipropylcadmium

2,3-dimethoxybenzoyl chloride

propyl bromide

Downstream raw materials:

1,2-Dimethoxy-3-(1-propyl-octyl)-benzene

3-(1-Propyl-octyl)-benzene-1,2-diol

1,2-Dimethoxy-3-[1-prop-(E)-ylidene-octyl]-benzene

(2,3-dihydroxyphenyl)propyl ketone

Refernces

• 1、 Albrecht, Markus,Mirtschin, Sebastian,De Groot, Marita,Janser, Ingo,Runsink, Jan,Raabe, Gerhard,Kogej, Michael,Schalley, Christoph A.,Froehlich, Roland. "Hierarchical assembly of helicate-type dinuclear titanium(IV) complexes". . p. 10371 - 10387. Retrieved 2007/10/03.