3-<3-(3-aminobenzamido)benzamido>benzamidopropionitrile

Base Information

• Chemical Name: 3-<3-(3-aminobenzamido)benzamido>benzamidopropionitrile
• CAS No.: 130270-28-9
• Molecular Formula: C₂₄H₂₁N₅O₃
• Molecular Weight: 427.462
• Mol file: 130270-28-9.mol

Synonyms:3-<3-(3-aminobenzamido)benzamido>benzamidopropionitrile

Chemical Property of 3-<3-(3-aminobenzamido)benzamido>benzamidopropionitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-<3-(3-aminobenzamido)benzamido>benzamidopropionitrile

There total 7 articles about 3-<3-(3-aminobenzamido)benzamido>benzamidopropionitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

3-<3-(3-nitrobenzamido)benzamido>benzamidopropionitrile (116507-49-4) → 3-<3-(3-aminobenzamido)benzamido>benzamidopropionitrile (130270-28-9)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; N,N-dimethyl-formamide; under 760 Torr; Ambient temperature;

Reference yield:

3-<3-nitrobenzamido>benzoic acid (106590-58-3) → 3-<3-(3-aminobenzamido)benzamido>benzamidopropionitrile (130270-28-9)

Guidance literature:

Multi-step reaction with 5 steps

1: SOCl₂

2: 82 percent / 4percent aq. NaHCO₃ / acetone / 12 h / Ambient temperature

3: SOCl₂

5: 65 percent / H₂ / 10percent Pd/C / dimethylformamide; methanol / 760 Torr / Ambient temperature

With thionyl chloride; hydrogen; sodium hydrogencarbonate; palladium on activated charcoal; In methanol; N,N-dimethyl-formamide; acetone;

Reference yield:

3-<3-nitrobenzamido>benzoyl chloride (16360-90-0) → 3-<3-(3-aminobenzamido)benzamido>benzamidopropionitrile (130270-28-9)

Guidance literature:

Multi-step reaction with 4 steps

1: 82 percent / 4percent aq. NaHCO₃ / acetone / 12 h / Ambient temperature

2: SOCl₂

4: 65 percent / H₂ / 10percent Pd/C / dimethylformamide; methanol / 760 Torr / Ambient temperature

With thionyl chloride; hydrogen; sodium hydrogencarbonate; palladium on activated charcoal; In methanol; N,N-dimethyl-formamide; acetone;

upstream raw materials:

3-<3-(3-nitrobenzamido)benzamido>benzamidopropionitrile

3-<3-nitrobenzamido>benzoic acid

3-<3-nitrobenzamido>benzoyl chloride

3-<3-(3-nitrobenzamido)benzamido>benzoic acid

Downstream raw materials:

3-<3-<3-(guanidinoacetamido)benzamido>benzamido>benzamidopropionamidine dihydrochloride

Refernces