α-ionone epoxyhydrazone

Base Information

• Chemical Name: α-ionone epoxyhydrazone
• CAS No.: 124572-59-4
• Molecular Formula: C₁₃H₂₂N₂O
• Molecular Weight: 222.33
• Mol file: 124572-59-4.mol

Synonyms:α-ionone epoxyhydrazone

Chemical Property of α-ionone epoxyhydrazone

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

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Technology Process of α-ionone epoxyhydrazone

There total 1 articles about α-ionone epoxyhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-[3-(2,6,6-trimethyl-cyclohex-2-enyl)-oxiranyl]-ethanone (37079-64-4) → α-ionone epoxyhydrazone (124572-59-4)

Guidance literature:

With hydrazine hydrate; acetic acid; In dichloromethane; at 0 ℃; for 48h; Yield given;

DOI:10.1016/S0040-4020(01)81022-X

Reference yield: 76.0%

α-ionone epoxyhydrazone (124572-59-4) → (Z)-2,6,6-Trimethyl-α-(1-propenyl)-2-cyclohexene-1-methanol (28102-24-1,28102-25-2,52610-46-5,145774-37-4,148021-15-2,148021-16-3)

Guidance literature:

With potassium tert-butylate; In tetrahydrofuran; pentane; at -100 ℃; for 1.5h; with KDA, too;

DOI:10.1016/S0040-4020(01)81022-X

Reference yield:

α-ionone epoxyhydrazone (124572-59-4) → alpha-ionone (127-41-3,6901-97-9,14398-36-8,24190-29-2,30685-95-1,31798-12-6,52340-45-1,67529-94-6,67529-95-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 76 percent / t-BuOK / tetrahydrofuran; pentane / 1.5 h / -100 °C / with KDA, too

2: periodinane / CH₂Cl₂ / Ambient temperature

With potassium tert-butylate; Dess-Martin periodane; In tetrahydrofuran; dichloromethane; pentane;

DOI:10.1016/S0040-4020(01)81022-X

upstream raw materials:

1-[3-(2,6,6-trimethyl-cyclohex-2-enyl)-oxiranyl]-ethanone

Downstream raw materials:

(Z)-2,6,6-Trimethyl-α-(1-propenyl)-2-cyclohexene-1-methanol

alpha-ionone

⁽²⁾-1-(2,6,6-trimethylcyclohex-2-en-1-yl)butan-1-one

Refernces