QAD-3

Base Information

• Chemical Name: QAD-3
• CAS No.: 937371-89-6
• Molecular Formula: C₂₉H₁₆Cl₂N₂O₆
• Molecular Weight: 559.362
• Mol file: 937371-89-6.mol

Synonyms:QAD-3

Chemical Property of QAD-3

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of QAD-3

There total 3 articles about QAD-3 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2,9-dichloroquinacridone (3089-17-6) + dimethyl 5-chloromethyl-1,3-benzenedicarboxylate (252210-01-8) → QAD-3 (937371-89-6)

Guidance literature:

2,9-dichloroquinacridone; With potassium tert-butylate; In dimethyl sulfoxide; at 110 ℃; for 1h;

dimethyl 5-chloromethyl-1,3-benzenedicarboxylate; In dimethyl sulfoxide; at 40 ℃; for 4h;

Reference yield:

1,3,5-tris-(methoxycarbonyl)benzene (2672-58-4) → QAD-3 (937371-89-6)

Guidance literature:

Multi-step reaction with 3 steps

1.1: lithium borohydride / acetic acid methyl ester; tetrahydrofuran / 3 h / 50 °C

2.1: thionyl chloride / N,N-dimethyl acetamide / toluene / 4 h / 40 °C

3.1: potassium tert-butylate / dimethyl sulfoxide / 1 h / 110 °C

3.2: 4 h / 40 °C

With lithium borohydride; thionyl chloride; potassium tert-butylate; N,N-dimethyl acetamide; In tetrahydrofuran; acetic acid methyl ester; dimethyl sulfoxide; toluene;

Reference yield:

dimethyl 5-hydroxymethylbenzene-1,3-dicarboxylate (109862-53-5) → QAD-3 (937371-89-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: thionyl chloride / N,N-dimethyl acetamide / toluene / 4 h / 40 °C

2.1: potassium tert-butylate / dimethyl sulfoxide / 1 h / 110 °C

2.2: 4 h / 40 °C

With thionyl chloride; potassium tert-butylate; N,N-dimethyl acetamide; In dimethyl sulfoxide; toluene;

upstream raw materials:

1,3,5-tris-(methoxycarbonyl)benzene

2,9-dichloroquinacridone

dimethyl 5-chloromethyl-1,3-benzenedicarboxylate

dimethyl 5-hydroxymethylbenzene-1,3-dicarboxylate

Refernces