1-Cyclooctylpiperazine

Base Information

• Chemical Name: 1-Cyclooctylpiperazine
• CAS No.: 21043-43-6
• Molecular Formula: C12H24N2
• Molecular Weight: 196.33
• Hs Code.: 2933599090
• European Community (EC) Number: 671-071-9
• DSSTox Substance ID: DTXSID20371002
• Wikidata: Q82158210
• Mol file: 21043-43-6.mol

Synonyms:1-cyclooctylpiperazine;21043-43-6;1-(cyclooctyl)piperazine;(1-Cyclooctyl)piperazine;SCHEMBL1267270;DTXSID20371002;WAA04343;BBL018671;MFCD01320900;STL194239;AKOS009157933;PS-5841;CS-0449520;FT-0638076;F14620;A815093

Chemical Property of 1-Cyclooctylpiperazine

Chemical Property:

• Boiling Point: 281.6 °C at 760 mmHg
• Flash Point: 102.5 °C
• PSA: 15.27000
• Density: 0.938 g/cm³
• LogP: 2.27120
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 196.193948774
• Heavy Atom Count: 14
• Complexity: 144

Purity/Quality:

98%min ^*data from raw suppliers

1-Cyclooctylpiperazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCCC(CCC1)N2CCNCC2

Technology Process of 1-Cyclooctylpiperazine

There total 1 articles about 1-Cyclooctylpiperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 1-cyclooctylpiperazine (21043-43-6)

Guidance literature:

entspr. N-Phenylpiperazin, 1) NaNO2/HCl, 2) SO2, Erhitz.;

Reference yield:

4-(4-chlorophenyl)-4-oxobutanoic acid (3984-34-7) + 1-cyclooctylpiperazine (21043-43-6) → 1-(4-chloro-phenyl)-4-(4-cyclooctyl-piperazin-1-yl)-butane-1,4-dione

Guidance literature:

4-(4-chlorophenyl)-4-oxobutanoic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 1.5h;

1-cyclooctylpiperazine; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃; for 4h;

DOI:10.1021/jm031028z