(2-phenyl)ethylsulfinylacetic acid

Base Information

• Chemical Name: (2-phenyl)ethylsulfinylacetic acid
• CAS No.: 860540-31-4
• Molecular Formula: C₁₀H₁₂O₃S
• Molecular Weight: 212.269
• Mol file: 860540-31-4.mol

Synonyms:(2-phenyl)ethylsulfinylacetic acid

Chemical Property of (2-phenyl)ethylsulfinylacetic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2-phenyl)ethylsulfinylacetic acid

There total 3 articles about (2-phenyl)ethylsulfinylacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.4%

→ (2-phenyl)ethylsulfinylacetic acid (860540-31-4)

Guidance literature:

With dihydrogen peroxide; In methanol; water; at 20 ℃;

Reference yield: 76.0%

NSC158362 (99186-25-1) → (2-phenyl)ethylsulfinylacetic acid (860540-31-4)

Guidance literature:

With dihydrogen peroxide; In methanol; water; at 20 ℃;

DOI:10.1021/jm500258v

Reference yield:

1-phenyl-2-bromoethane (103-63-9) → (2-phenyl)ethylsulfinylacetic acid (860540-31-4)

Guidance literature:

Multi-step reaction with 2 steps

1: aq.-ethanolic NaOH / 20 °C

2: aqueous Na₂CO₃; K₂S₂O₈

With sodium hydroxide; dipotassium peroxodisulfate; sodium carbonate;

upstream raw materials:

NSC₁₅₈₃₆₂

1-phenyl-2-bromoethane

Downstream raw materials:

E-acetic acid 2-acetoxy-4-[2-(2-phenylethanesulfinyl)vinyl]-phenyl ester

Glyoxilic acid

2-mercaptophenylethane

Refernces

• 1、 Ning, Xianling,Guo, Ying,Wang, Xiaowei,Ma, Xiaoyan,Tian, Chao,Shi, Xueqi,Zhu, Renzong,Cheng, Can,Du, Yansheng,Ma, Zhizhong,Zhang, Zhili,Liu, Junyi. "Design, synthesis, and biological evaluation of (E)-3,4-dihydroxystyryl aralkyl sulfones and sulfoxides as novel multifunctional neuroprotective agents". . p. 4302 - 4312. Retrieved 2014/06/09.