N-Benzylnaphthalen-2-amine

Base Information

• Chemical Name: N-Benzylnaphthalen-2-amine
• CAS No.: 13672-18-9
• Molecular Formula: C17H15N
• Molecular Weight: 233.313
• Hs Code.: 2921499090
• European Community (EC) Number: 678-236-4
• DSSTox Substance ID: DTXSID20500077
• Nikkaji Number: J81.658B
• Mol file: 13672-18-9.mol

Synonyms:N-Benzylnaphthalen-2-amine;13672-18-9;N-Benzyl-2-naphthylamine;2-Naphthalenamine, N-(phenylmethyl)-;2-Naphthalenamine,N-(phenylmethyl)-;N-BENZYL-B-NAPHTHYL-AMINE;N-Benzyl-beta-naphthyl-amine;N-BENZYL-B-NAPHTHylamine;SCHEMBL1542592;DTXSID20500077;MFCD00144848;AKOS009062231;CS-W012924;FD10523;SB66549;AS-62931;B3088;FT-0724997;A886646

Chemical Property of N-Benzylnaphthalen-2-amine

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 68 °C
• Refractive Index: 1.694
• Boiling Point: 406.307 °C at 760 mmHg
• PKA: 4.13±0.50(Predicted)
• Flash Point: 215.501 °C
• PSA: 12.03000
• Density: 1.145 g/cm³
• LogP: 4.52490
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• XLogP3: 4.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 233.120449483
• Heavy Atom Count: 18
• Complexity: 244

Purity/Quality:

98%,99%, ^*data from raw suppliers

N-Benzyl-2-naphthylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)CNC2=CC3=CC=CC=C3C=C2

Technology Process of N-Benzylnaphthalen-2-amine

There total 22 articles about N-Benzylnaphthalen-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-bromonaphthalene (580-13-2) + benzylamine (100-46-9) → benzyl-2-naphthylamine (13672-18-9)

Guidance literature:

With potassium phosphate; copper(l) iodide; CVT-2537; In dimethyl sulfoxide; at 90 ℃; for 24h; Inert atmosphere;

DOI:10.1021/ol301135c

Reference yield: 99.0%

benzaldehyde (100-52-7) + naphthalen-2-ylamine (91-59-8) → benzyl-2-naphthylamine (13672-18-9)

Guidance literature:

With (2,6-dichlorophenyl)bis(2,3,5,6-tetrafluorophenyl)borane; hydrogen; In tetrahydrofuran; at 100 ℃; for 6h; under 15201 Torr; Sealed tube; Molecular sieve; Autoclave; Green chemistry;

DOI:10.1021/jacs.8b03626

Reference yield: 97.0%

2-chloronaphthalene (91-58-7) + benzylamine (100-46-9) → benzyl-2-naphthylamine (13672-18-9)

Guidance literature:

With potassium phosphate; copper(l) iodide; N¹,N²-bis(2,4,6-trimethoxyphenyl)oxalamide; In dimethyl sulfoxide; at 120 ℃; for 24h; Inert atmosphere; Schlenk technique;

DOI:10.1021/jacs.5b08411

upstream raw materials:

benzylidene(2-naphthyl)amine

benzaldehyde

naphthalen-2-ylamine

benzyl alcohol

Downstream raw materials:

N-benzyl-N-[2]naphthyl-hydrazine

benzyl-[2]naphthyl-nitroso-amine

2-phenylnaphtho[2,1-d]thiazole

Refernces

• 1、 Vershinin, Vlada,Forkosh, Hagit,Ben-Lulu, Mor,Libman, Anna,Pappo, Doron. "Mechanistic Insights into the FeCl3-Catalyzed Oxidative Cross-Coupling of Phenols with 2-Aminonaphthalenes". . p. 79 - 90. Retrieved 2020/12/23.
• 2、 Wu, Di,Bu, Qingqing,Guo, Cheng,Dai, Bin,Liu, Ning. "Cooperative catalysis of molybdenum with organocatalysts for distribution of products between amines and imines". . . Retrieved 2021/02/02.