5-amino-2-hexylphenol

Base Information

• Chemical Name: 5-amino-2-hexylphenol
• CAS No.: 408507-86-8
• Molecular Formula: C₁₂H₁₉NO
• Molecular Weight: 193.289
• Mol file: 408507-86-8.mol

Synonyms:5-amino-2-hexylphenol

Chemical Property of 5-amino-2-hexylphenol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-amino-2-hexylphenol

There total 5 articles about 5-amino-2-hexylphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

N-(4-hexyl-3-hydroxy-phenyl)-acetamide → 5-amino-2-hexylphenol (408507-86-8)

Guidance literature:

With potassium hydroxide; In methanol; water; at 100 ℃; for 3.5h;

DOI:10.1016/j.ijpharm.2010.06.036

Reference yield:

4-Hexylresorcinol (136-77-6) → 5-amino-2-hexylphenol (408507-86-8)

Guidance literature:

With ammonium hydroxide; ammonium chloride; sodium hydrogensulfite; at 250 ℃;

DOI:10.1021/ja01847a041

Reference yield:

C14H19NO3 → 5-amino-2-hexylphenol (408507-86-8)

Guidance literature:

Multi-step reaction with 3 steps

1: aluminum (III) chloride; sodium chloride / 135 °C

2: palladium on activated charcoal; methanesulfonic acid; hydrogen; acetic acid / ethanol; ethyl acetate

3: potassium hydroxide / methanol; water / 3.5 h / 100 °C

With aluminum (III) chloride; methanesulfonic acid; palladium on activated charcoal; hydrogen; acetic acid; sodium chloride; potassium hydroxide; In methanol; ethanol; water; ethyl acetate;

DOI:10.1016/j.ijpharm.2010.06.036

upstream raw materials:

4-Hexylresorcinol

Downstream raw materials:

[3-(tert-butyldiphenylsiloxy)-4-hexylphenyl]-(6-chloro-9H-purin-2-yl)-amine

(2-{2-[3-(tert-butyldiphenylsiloxy)-4-hexylphenylamino]-6-chloro-purin-9-yl}-ethoxymethyl)-phosphonic acid diethyl ester

{2-[6-chloro-2-(4-hexyl-3-hydroxyphenylamino)-purin-9-yl]-ethoxymethyl}-phosphonic acid diethyl ester

{2-[6-amino-2-(4-hexyl-3-hydroxy-phenylamino)-purin-9-yl]-ethoxymethyl}-phosphonic acid

Refernces