Technology Process of 3-(2-aminophenyl)-2,1-benzisothiazole
There total 4 articles about 3-(2-aminophenyl)-2,1-benzisothiazole which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
pyridine; N-sulfinylmethanesulfonamide;
In
benzene;
for 48h;
Heating;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 52 percent / tin, conc. HCl / ethanol / 1 h / Heating
2: 21 percent / N-sulfinylmethanesulfonamide, pyridine / benzene / 48 h / Heating
With
pyridine; hydrogenchloride; N-sulfinylmethanesulfonamide; tin;
In
ethanol; benzene;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 93 percent / sulfuric acid, nitric acid / -40 °C
2: 1) sodium nitrite, sulfuric acid; 2) copper(I) oxide, ethanol / 1) acetic acid, 18 deg C, 1 h.; 2) 60 deg C, 80 min.
3: 52 percent / tin, conc. HCl / ethanol / 1 h / Heating
4: 21 percent / N-sulfinylmethanesulfonamide, pyridine / benzene / 48 h / Heating
With
pyridine; copper(I) oxide; hydrogenchloride; N-sulfinylmethanesulfonamide; tin; ethanol; sulfuric acid; nitric acid; sodium nitrite;
In
ethanol; benzene;
