2-(4-Hydroxyphenyl)-3-methyl-1-[4-[2-(1-piperidinyl)ethoxy]benzyl]-1H-indol-5-ol hydrochloride hydrate

Base Information

• Chemical Name: 2-(4-Hydroxyphenyl)-3-methyl-1-[4-[2-(1-piperidinyl)ethoxy]benzyl]-1H-indol-5-ol hydrochloride hydrate
• CAS No.: 389125-71-7
• Molecular Formula: C29H32N2O3^.HCl^.H2O
• Molecular Weight: 511.05
• Mol file: 389125-71-7.mol

Synonyms:1H-Indol-5-ol,2-(4-hydroxyphenyl)-3-methyl-1-[[4-[2-(1-piperidinyl)ethoxy]phenyl]methyl]-,monohydrochloride, monohydrate (9CI);Pipindoxifene hydrochloride monohydrate;

Chemical Property of 2-(4-Hydroxyphenyl)-3-methyl-1-[4-[2-(1-piperidinyl)ethoxy]benzyl]-1H-indol-5-ol hydrochloride hydrate

Chemical Property:

• Vapor Pressure: 1.93E-19mmHg at 25°C
• Boiling Point: 685.8 °C at 760 mmHg
• Flash Point: 368.6 °C
• PSA: 67.09000
• LogP: 6.61650

Purity/Quality:

98%Min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(4-Hydroxyphenyl)-3-methyl-1-[4-[2-(1-piperidinyl)ethoxy]benzyl]-1H-indol-5-ol hydrochloride hydrate

There total 1 articles about 2-(4-Hydroxyphenyl)-3-methyl-1-[4-[2-(1-piperidinyl)ethoxy]benzyl]-1H-indol-5-ol hydrochloride hydrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

Pipendoxifene hydrochloride (245124-69-0) → 2-(4-hydroxyphenyl)-3-methyl-1-[4-(2-piperidin-1-yl-ethoxy)-benzyl]-1H-indol-5-ol hydrochloride monohydrate (389125-71-7)

Guidance literature:

In ethanol; water; at 22 - 80 ℃; for 7h; Product distribution / selectivity;

upstream raw materials:

Pipendoxifene hydrochloride

Refernces

• 1、 -. "Crystalline polymorph of pipindoxifene hydrochloride monohydrate". Page/Page column 5. . Retrieved 2008/06/13.