3-beta-Hydroxy-olean-12-en-28-oic acid butyrate

Base Information

• Chemical Name: 3-beta-Hydroxy-olean-12-en-28-oic acid butyrate
• CAS No.: 107660-10-6
• Molecular Formula: C₃₄H₅₄O₄
• Molecular Weight: 526.8
• Mol file: 107660-10-6.mol

Synonyms:Olean-12-en-28-oicacid, 3b-hydroxy-, butyrate (7CI);

Chemical Property of 3-beta-Hydroxy-olean-12-en-28-oic acid butyrate

Chemical Property:

• Refractive Index: 1.541
• Boiling Point: 586.6 °C at 760 mmHg
• Flash Point: 174.3 °C
• PSA: 63.60000
• Density: 1.08 g/cm³
• LogP: 8.58460

Purity/Quality:

HPLC≥98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-beta-Hydroxy-olean-12-en-28-oic acid butyrate

There total 4 articles about 3-beta-Hydroxy-olean-12-en-28-oic acid butyrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

butanoic acid anhydride (106-31-0) + Oleanolic acid (508-02-1) → 3β-butyryloxyoleanane-12-en-28-carboxylic acid (107660-10-6)

Guidance literature:

With pyridine; at 20 ℃; for 24h;

DOI:10.1016/j.ejmech.2013.12.049

Reference yield: 68.0%

pentanoic anhydride (2082-59-9) + Oleanolic acid (508-02-1) → 3β-butyryloxyoleanane-12-en-28-carboxylic acid (107660-10-6)

Guidance literature:

pentanoic anhydride; Oleanolic acid; With pyridine; dmap; In dichloromethane; at 20 ℃; for 10h;

With oxalyl dichloride; In dichloromethane; at 60 ℃; for 0.5h;

Reference yield:

Oleanolic acid (508-02-1) + butyric acid (107-92-6) → C34H54O4 (107660-10-6)

Guidance literature:

butyric acid; With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In chloroform; at 20 ℃;

Oleanolic acid; With dmap; In chloroform; at 20 ℃;

upstream raw materials:

Oleanolic acid

butanoic acid anhydride

pentanoic anhydride

butyric acid

Refernces

• 1、 -. "Oleanolic acid-miazines conjugate and its preparation method and application". Paragraph 0278; 0279. . Retrieved 2016/10/08.
• 2、 Parra, Andres,Martin-Fonseca, Samuel,Rivas, Francisco,Reyes-Zurita, Fernando J.,Medina-O'Donnell, Marta,Martinez, Antonio,Garcia-Granados, Andres,Lupia?ez, Jose A.,Albericio, Fernando. "Semi-synthesis of acylated triterpenes from olive-oil industry wastes for the development of anticancer and anti-HIV agents". . p. 278 - 301. Retrieved 2014/02/14.