2'-BENZYLOXYACETOPHENONE

Base Information

• Chemical Name: 2'-BENZYLOXYACETOPHENONE
• CAS No.: 31165-67-0
• Molecular Formula: C15H14O2
• Molecular Weight: 226.275
• Hs Code.: 2914509090
• Mol file: 31165-67-0.mol

Synonyms:Acetophenone,2'-(benzyloxy)- (6CI,7CI,8CI);1-(2-Benzyloxyphenyl)ethanone;1-[2-(Phenylmethoxy)phenyl]ethanone;2-Benzyloxyacetophenone;2'-(Benzyloxy)acetophenone;

Chemical Property of 2'-BENZYLOXYACETOPHENONE

Chemical Property:

• Vapor Pressure: 3.06E-05mmHg at 25°C
• Melting Point: 38 °C
• Refractive Index: 1.569
• Boiling Point: 355.767 °C at 760 mmHg
• Flash Point: 157.028 °C
• PSA: 26.30000
• Density: 1.1 g/cm³
• LogP: 3.46820
• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

2''-Benzyloxyacetophenone ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2'-BENZYLOXYACETOPHENONE

There total 9 articles about 2'-BENZYLOXYACETOPHENONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

o-hydroxyacetophenone (118-93-4,104809-67-8) + benzyl chloride (100-44-7) → 2'-benzyloxyacetophenone (31165-67-0)

Guidance literature:

With potassium carbonate; In acetone; for 12h; Heating;

DOI:10.1021/ol035786v

Reference yield: 99.0%

benzyl bromide (100-39-0) + o-hydroxyacetophenone (118-93-4,104809-67-8) → 2'-benzyloxyacetophenone (31165-67-0)

Guidance literature:

With potassium carbonate; potassium iodide; In acetone; Heating;

DOI:10.1021/ol034806q

Reference yield: 93.0%

o-hydroxyacetophenone (118-93-4,104809-67-8) + iodomethylbenzene (620-05-3) → 2'-benzyloxyacetophenone (31165-67-0)

Guidance literature:

With potassium carbonate; In acetone;

DOI:10.1016/S0040-4039(00)85808-6

upstream raw materials:

o-hydroxyacetophenone

benzyl chloride

o-(benzyloxy)valerophenone

benzyl bromide

Downstream raw materials:

1-(2-benzyloxyphenyl)-3-(6-benzodioxan-1,4-yl)propenone

1-(2-Benzyloxyphenyl)-3-(2-methyl-4-thiazolyl)-1-propenone

6-(2-benzyloxy-phenyl)-2-hydroxy-4-(3-nitro-phenyl)-nicotinonitrile

6-(2-Benzyloxy-phenyl)-2-hydroxy-4,6,-dioxo-hex-2-enoic Acid Methyl Ester

Refernces

• 1、 Neidlein,Gehringer. "". . p. 232,233. Retrieved 1974.
• 2、 -. "Application of iron (III) complex containing 1,3-di-tert-butyl imidazole cations in synthesis of aryl benzyl ether compounds". Paragraph 0026-0027. . Retrieved 2021/04/26.
• 3、 Bouhedja, Mourad,Peres, Basile,Fhayli, Wassim,Ghandour, Zeinab,Boumendjel, Ahcène,Faury, Gilles,Khelili, Smail. "Design, synthesis and biological evaluation of novel ring-opened cromakalim analogues with relaxant effects on vascular and respiratory smooth muscles and as stimulators of elastin synthesis". . p. 774 - 796. Retrieved 2018/01/05.