4-Benzoylphenyl methyl sulfoxide

Base Information

• Chemical Name: 4-Benzoylphenyl methyl sulfoxide
• CAS No.: 73241-57-3
• Molecular Formula: C14H12O2S
• Molecular Weight: 244.314
• DSSTox Substance ID: DTXSID20503149
• Nikkaji Number: J736.308G
• Mol file: 73241-57-3.mol

Synonyms:4-BENZOYLPHENYL METHYL SULFOXIDE;73241-57-3;(4-methylsulfinylphenyl)-phenylmethanone;SCHEMBL8065192;DTXSID20503149;[4-(Methanesulfinyl)phenyl](phenyl)methanone

Chemical Property of 4-Benzoylphenyl methyl sulfoxide

Chemical Property:

• Vapor Pressure: 1.13E-07mmHg at 25°C
• Melting Point: 82-88 °C
• Refractive Index: 1.653
• Boiling Point: 432.2 °C at 760 mmHg
• Flash Point: 215.2 °C
• PSA: 53.35000
• Density: 1.28 g/cm³
• LogP: 3.52070
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 244.05580079
• Heavy Atom Count: 17
• Complexity: 287

Purity/Quality:

98%Min ^*data from raw suppliers

4-Benzoylphenyl methylsulfoxide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CS(=O)C1=CC=C(C=C1)C(=O)C2=CC=CC=C2

Technology Process of 4-Benzoylphenyl methyl sulfoxide

There total 3 articles about 4-Benzoylphenyl methyl sulfoxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

4-methylthiobenzophenone (23405-48-3) → (4-Methanesulfinyl-phenyl)-phenyl-methanone (73241-57-3)

Guidance literature:

With tert.-butylnitrite; In water; acetonitrile; at 25 ℃; for 8h; chemoselective reaction; Green chemistry;

DOI:10.1016/j.tetlet.2018.07.001

Reference yield:

1-phenyl-1-(4-methylthiophenyl)ethylene (138534-58-4) → 4-methylthiobenzophenone (23405-48-3) + (4-Methanesulfinyl-phenyl)-phenyl-methanone (73241-57-3)

Guidance literature:

With oxygen; In chloroform; at 20 ℃; for 24h; Overall yield = 87 percentSpectr.; Sealed tube; Irradiation; Green chemistry;

DOI:10.1002/cssc.202101504

Reference yield:

1-phenyl-1-(4-methylthiophenyl)ethylene (138534-58-4) → (4-Methanesulfinyl-phenyl)-phenyl-methanone (73241-57-3)

Guidance literature:

Multi-step reaction with 2 steps

1: oxygen / chloroform / 12 h / 20 °C / Sealed tube; Irradiation; Green chemistry

2: oxygen / chloroform / 24 h / 20 °C / Sealed tube; Irradiation; Green chemistry

With oxygen; In chloroform;

DOI:10.1002/cssc.202101504

upstream raw materials:

4-methylthiobenzophenone

1-phenyl-1-(4-methylthiophenyl)ethylene

Downstream raw materials:

4-(4-methoxy-phenyl)-benzophenone

Refernces

• 1、 Li, Jianing,Zhao, Jingnan,Ma, Cunfei,Yu, Zongyi,Zhu, Hongfei,Yun, Lei,Meng, Qingwei. "Visible-Light-Driven Oxidative Cleavage of Alkenes Using Water-Soluble CdSe Quantum Dots". . p. 4985 - 4992. Retrieved 2021/10/16.