alpha-(Benzoylamino)-4-(benzoyloxy)-N,N-dipropylbenzenepropanamide

Base Information

• Chemical Name: alpha-(Benzoylamino)-4-(benzoyloxy)-N,N-dipropylbenzenepropanamide
• CAS No.: 57227-08-4
• Molecular Formula: C29H32 N2 O4
• Molecular Weight: 472.584
• Mol file: 57227-08-4.mol

Synonyms:Benzenepropanamide,a-(benzoylamino)-4-(benzoyloxy)-N,N-dipropyl-,(?à)-

Chemical Property of alpha-(Benzoylamino)-4-(benzoyloxy)-N,N-dipropylbenzenepropanamide

Chemical Property:

• Boiling Point: 690.0±55.0 °C(Predicted)
• PKA: 13.45±0.46(Predicted)
• PSA: 75.71000
• Density: 1.150
• LogP: 5.28640
• Storage Temp.: Refrigerator
• Solubility.: Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly), Methanol (Sligh

Purity/Quality:

99% ^*data from raw suppliers

N,O-Dibenzoyl-DL-tyrosyl-N’,N’-dipropylamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: N,O-Dibenzoyl-DL-tyrosyl-N',N'-dipropylamide is a metabolite of the antispasmodic agent Tiropramide (T446900). Tiropramide impurity B. N,O-Dibenzoyl-DL-tyrosyl-N'',N''-dipropylamide is a metabolite of the antispasmodic agent Tiropramide (T446900). Tiropramide impurity B.

Technology Process of alpha-(Benzoylamino)-4-(benzoyloxy)-N,N-dipropylbenzenepropanamide

There total 4 articles about alpha-(Benzoylamino)-4-(benzoyloxy)-N,N-dipropylbenzenepropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

L-tyrosine (60-18-4,18875-48-4,25619-78-7,30704-25-7) → O.N-Dibenzoyl-DL-tyrosyl-di-n-propylamid (57227-08-4)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydroxide

2: (i) Et₃N, ClCO₂Et, (ii) /BRN= 505974/

With sodium hydroxide;

Reference yield:

benzoyl chloride (98-88-4) → O.N-Dibenzoyl-DL-tyrosyl-di-n-propylamid (57227-08-4)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydroxide

2: (i) Et₃N, ClCO₂Et, (ii) /BRN= 505974/

With sodium hydroxide;

Reference yield:

N-benzoyl-O-benzoyl-L-tyrosine (14325-35-0) + di-n-propylamine (142-84-7) → O.N-Dibenzoyl-DL-tyrosyl-di-n-propylamid (57227-08-4)

Guidance literature:

Multistep reaction; (i) Et₃N, ClCO₂Et, (ii) /BRN= 505974/;

upstream raw materials:

N-benzoyl-O-benzoyl-L-tyrosine

di-n-propylamine

L-tyrosine

benzoyl chloride

Downstream raw materials:

N-benzoyl-DL-tyrosil-di-n-propylamide

Alfospas