(4aR,4bS,7S,9aS,9bS,11aR)-N-tert-Butyl-4a-methyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide

Base Information Edit

Chemical Name:(4aR,4bS,7S,9aS,9bS,11aR)-N-tert-Butyl-4a-methyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide
CAS No.:166896-74-8
Molecular Formula:C23H36N2O2
Molecular Weight:372.551
Hs Code.:
DSSTox Substance ID:DTXSID20704876
Mol file:166896-74-8.mol

(4aR,4bS,7S,9aS,9bS,11aR)-N-tert-Butyl-4a-methyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide

Synonyms:DTXSID20704876;AKOS025402206;AC-6220;(4aR,4bS,7S,9aS,9bS,11aR)-N-tert-Butyl-4a-methyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide

Suppliers and Price of (4aR,4bS,7S,9aS,9bS,11aR)-N-tert-Butyl-4a-methyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

TRC
(4aR,4bS,6aS,7S,9aS,9bS)-N-(1,1-Dimethylethyl)-2,3,4,4a,4b,5,6,6a,7,8,9,9a,9b,10-tetradecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxamide
10mg
$ 1320.00

Total 76 raw suppliers

Chemical Property of (4aR,4bS,7S,9aS,9bS,11aR)-N-tert-Butyl-4a-methyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide Edit

Chemical Property:

Melting Point:289-293 °C
Refractive Index:1.523
Boiling Point:588.477 °C at 760 mmHg
PKA:15.44±0.70(Predicted)
Flash Point:182.971 °C
Density:1.106 g/cm³
XLogP3:2.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:358.262028332
Heavy Atom Count:26
Complexity:635

Purity/Quality:

99% ^*data from raw suppliers

(4aR,4bS,6aS,7S,9aS,9bS)-N-(1,1-Dimethylethyl)-2,3,4,4a,4b,5,6,6a,7,8,9,9a,9b,10-tetradecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC12C=CC(=O)NC1CCC3C2CCC4C3CCC4C(=O)NC(C)(C)C
Isomeric SMILES:C[C@]12C=CC(=O)N[C@@H]1CC[C@@H]3[C@@H]2CCC4[C@H]3CC[C@@H]4C(=O)NC(C)(C)C
Uses (4aR,4bS,6aS,7S,9aS,9bS)-N-(1,1-Dimethylethyl)-2,3,4,4a,4b,5,6,6a,7,8,9,9a,9b,10-tetradecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxamide, is an impurity of Finasteride (F342000), Inhibitor of 5α-reductase, the enzyme which converts testosterone to the more potent androgen, 5α-dihydrotestosterone.Antialopecia agent.

Technology Process of (4aR,4bS,7S,9aS,9bS,11aR)-N-tert-Butyl-4a-methyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide

There total 6 articles about (4aR,4bS,7S,9aS,9bS,11aR)-N-tert-Butyl-4a-methyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.7%