3-Deoxy-D-manno-2-octulosonic acid ammonium salt

Base Information

• Chemical Name: 3-Deoxy-D-manno-2-octulosonic acid ammonium salt
• CAS No.: 103404-70-2
• Molecular Formula: C₈H₁₄O₈*H₃N
• Molecular Weight: 255.225
• Hs Code.: 29329990
• Mol file: 103404-70-2.mol

Synonyms:3-Deoxy-2-octulosonic acid monoammonium salt; KDO ammonium salt;

Chemical Property of 3-Deoxy-D-manno-2-octulosonic acid ammonium salt

Chemical Property:

• Appearance/Colour: white crystalline solid
• Vapor Pressure: 6.33E-20mmHg at 25°C
• Melting Point: 122-124 °C
• Boiling Point: 654.8 °C at 760 mmHg
• Flash Point: 349.8 °C
• PSA: 150.92000
• LogP: -3.05260
• Storage Temp.: −20°C
• Solubility.: DMSO (Slightly, Heated), Methanol (Very Slightly), Water (Slightly)

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-Deoxy-D-manno-2-octulosonic Acid, Ammonium Salt ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A ketosidic component in all lipopolysaccharides of Gram-negative bacteria and has been identified in several acidic exopolysaccharides (K-antigens). Synthetic analogues of KDO may be studied for their potential to disrupt the biosynthesis of bacterial cell-wall components, and lead to new antibacterial agents. 3-Deoxy-D-manno-2-octulosonic Acid Ammonium Salt is a ketosidic component in all lipopolysaccharides of Gram-negative bacteria and has been identified in several acidic exopolysaccharides (K-antigens). Synthetic analogues of KDO may be studied for their potential to disrupt the biosynthesis of bacterial cell-wall components, and lead to new antibacterial agents.

Technology Process of 3-Deoxy-D-manno-2-octulosonic acid ammonium salt

There total 4 articles about 3-Deoxy-D-manno-2-octulosonic acid ammonium salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 21.0%

Oxalacetic acid (328-42-7) + D-lyxose (1114-34-7) → ammonium-2-keto-3-deoxy-D-lyxooctulosonate (20595-77-1,20603-30-9,25539-49-5,103404-70-2,123672-57-1)

Guidance literature:

With potassium hydroxide; In water; for 2h; Ambient temperature;

Reference yield: 18.0%

Oxalacetic acid (328-42-7) + D-ribose (50-69-1) → ammonium-2-keto-3-deoxy-D-ribooctulosonate (20595-77-1,20603-30-9,25539-49-5,103404-70-2,123672-57-1)

Guidance literature:

With potassium hydroxide; In water; for 2h; Ambient temperature;

Reference yield: 17.0%

Oxalacetic acid (328-42-7) + L-arabinose (5328-37-0) → ammonium-2-keto-3-deoxy-L-arabinooctulosonate (20595-77-1,20603-30-9,25539-49-5,103404-70-2,123672-57-1)

Guidance literature:

With potassium hydroxide; In water; for 2h; Ambient temperature;

upstream raw materials:

Oxalacetic acid

D-lyxose

D-ribose

D-xylose

Refernces