2-HEPTYLBENZIMIDAZOLE

Base Information

• Chemical Name: 2-HEPTYLBENZIMIDAZOLE
• CAS No.: 5851-49-0
• Molecular Formula: C14H20N2
• Molecular Weight: 216.326
• Hs Code.: 2933990090
• Mol file: 5851-49-0.mol

Synonyms:Benzimidazole,2-heptyl- (7CI,8CI);2-Heptyl-1H-benzimidazole;2-Heptylbenzimidazole;2-n-Heptylbenzimidazole;

Chemical Property of 2-HEPTYLBENZIMIDAZOLE

Chemical Property:

• Vapor Pressure: 5.28E-06mmHg at 25°C
• Refractive Index: 1.572
• Boiling Point: 392.2 °C at 760 mmHg
• Flash Point: 193 °C
• PSA: 28.68000
• Density: 1.027 g/cm³
• LogP: 4.07580
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

2-Heptyl-1H-benzo[d]imidazole 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-HEPTYLBENZIMIDAZOLE

There total 14 articles about 2-HEPTYLBENZIMIDAZOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

octanol (111-87-5) + 1,2-diamino-benzene (95-54-5) → 2-heptyl-1H-benzoimidazole (5851-49-0)

Guidance literature:

With [Py(NP(iPr)₂)(NHP(iPr)₂)Ir(cod)]; potassium tert-butylate; In diethylene glycol dimethyl ether; at 110 ℃; for 24h; Inert atmosphere;

DOI:10.1002/chem.201400400

Reference yield: 90.0%

Octanal (124-13-0) + 1,2-diamino-benzene (95-54-5) → 2-heptyl-1H-benzoimidazole (5851-49-0)

Guidance literature:

With tetradecane; In 1,3,5-trimethyl-benzene; for 14h; Inert atmosphere; Reflux;

DOI:10.1016/j.tetlet.2015.06.073

Reference yield: 88.0%

Tri-n-octylamine (1116-76-3) + 1,2-diamino-benzene (95-54-5) → 2-heptyl-1H-benzoimidazole (5851-49-0)

Guidance literature:

With diphenyl-phosphinic acid; oxygen; In 1,4-dioxane; at 115 ℃; for 12h; under 760.051 Torr; Schlenk technique;

DOI:10.1039/c4ob00578c

upstream raw materials:

Octanoic acid

1,2-diamino-benzene

n-octyne

methyl octanate

Refernces

• 1、 Zuo, Minghui,Guo, Weihao,Pang, Yucheng,Guo, Rui,Hou, Chuanfu,Sun, Shouneng,Wu, Hongfeng,Sun, Zhizhong,Chu, Wenyi. "Direct synthesis of 2-substituted benzimidazoles: Via dehydrogenative coupling of aromatic-diamine and primary alcohol catalyzed by a Co complex". . p. 14490 - 14495. Retrieved 2020/10/03.
• 2、 Goswami, Mridusmita,Dutta, Mintu Maan,Phukan, Prodeep. "Sulfonic-acid-functionalized activated carbon made from tea leaves as green catalyst for synthesis of 2-substituted benzimidazole and benzothiazole". . p. 1597 - 1615. Retrieved 2017/11/17.