Technology Process of C16H13ClO3
There total 8 articles about C16H13ClO3 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
4-{[tert-butyl(dimethyl)silyl]oxy}-2-chlorobenzaldehyde;
With
sodium hydride;
In
tetrahydrofuran; mineral oil;
at 0 ℃;
for 0.5h;
3-(diethyoxyphosphorylmethyl)benzoic acid methyl ester;
In
tetrahydrofuran; mineral oil;
at 0 - 20 ℃;
With
ammonium chloride;
In
tetrahydrofuran; mineral oil;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: triethylamine / dmap / dichloromethane / 1 h / 20 °C
2.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 °C
2.2: 0 - 20 °C
With
sodium hydride; triethylamine;
dmap;
In
tetrahydrofuran; dichloromethane; mineral oil;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium carbonate; calcium hydroxide / water / 3 h / Reflux; Inert atmosphere
2.1: triethylamine / dmap / dichloromethane / 1 h / 20 °C
3.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 °C
3.2: 0 - 20 °C
With
sodium hydride; sodium carbonate; triethylamine; calcium hydroxide;
dmap;
In
tetrahydrofuran; dichloromethane; water; mineral oil;