geronic acid-d₆

Base Information

• Chemical Name: geronic acid-d₆
• CAS No.: 1584651-49-9
• Molecular Formula: C₉H₁₆O₃
• Molecular Weight: 178.177
• Mol file: 1584651-49-9.mol

Synonyms:geronic acid-d₆

Chemical Property of geronic acid-d₆

Chemical Property:

Purity/Quality:

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Technology Process of geronic acid-d₆

There total 1 articles about geronic acid-d₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

2-<(2)H3>methyl-<3,3,3-(2)H3>propanoic acid (29054-08-8) + 2,2-dimethoxy-5-chloropentane (56519-61-0) → geronic acid-d6 (1584651-49-9)

Guidance literature:

2-<(2)H3>methyl-<3,3,3-(2)H3>propanoic acid; With sodium hydride; In tetrahydrofuran; mineral oil; at 20 ℃; Inert atmosphere; Reflux;

With lithium diisopropyl amide; In tetrahydrofuran; n-heptane; ethylbenzene; mineral oil; at 0 - 35 ℃; Inert atmosphere;

2,2-dimethoxy-5-chloropentane; In tetrahydrofuran; n-heptane; ethylbenzene; mineral oil; at 0 - 35 ℃; for 2.75h; Inert atmosphere;

DOI:10.1139/cjc-2013-0494

upstream raw materials:

2-<(2)H3>methyl-<3,3,3-(2)H3>propanoic acid

2,2-dimethoxy-5-chloropentane

Refernces