3'-O-(1-phenyltetrazol-5-yl)diosmin

Base Information

• Chemical Name: 3'-O-(1-phenyltetrazol-5-yl)diosmin
• CAS No.: 771480-96-7
• Molecular Formula: C₃₅H₃₆N₄O₁₅
• Molecular Weight: 752.689
• Mol file: 771480-96-7.mol

Synonyms:3'-O-(1-phenyltetrazol-5-yl)diosmin

Chemical Property of 3'-O-(1-phenyltetrazol-5-yl)diosmin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3'-O-(1-phenyltetrazol-5-yl)diosmin

There total 1 articles about 3'-O-(1-phenyltetrazol-5-yl)diosmin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

5-Chloro-1-phenyltetrazole (14210-25-4) + diosmin (520-27-4) → 3'-O-(1-phenyltetrazol-5-yl)diosmin (771480-96-7)

Guidance literature:

With potassium hydrogencarbonate; In N,N-dimethyl-formamide; at 80 ℃; for 2h;

DOI:10.1021/np040079b

Reference yield: 53.0%

3'-O-(1-phenyltetrazol-5-yl)diosmin (771480-96-7) → acacetin 7-O-rutinoside (480-36-4)

Guidance literature:

With ammonium formate; palladium on activated charcoal; In methanol; for 5h; Heating;

DOI:10.1021/np040079b

Reference yield:

3'-O-(1-phenyltetrazol-5-yl)diosmin (771480-96-7) → 5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-chromen-4-one (5128-44-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 53 percent / HCOONH₄ / Pd/C / methanol / 5 h / Heating

2: 70 percent / aq. HCl / 1.5 h / 50 - 55 °C

3: 95 percent / K₂CO₃ / dimethylformamide / 20 °C

With hydrogenchloride; ammonium formate; potassium carbonate; palladium on activated charcoal; In methanol; N,N-dimethyl-formamide;

DOI:10.1021/np040079b

upstream raw materials:

5-Chloro-1-phenyltetrazole

diosmin

Downstream raw materials:

acacetin 7-O-rutinoside

7,4'-dimethoxy-5-hydroxy-6-iodoflavone

5,7-dihydroxy-2-(4'-methoxyphenyl)-4H-1-benzopyran-4-one

5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-chromen-4-one

Refernces