1-Iodo-2-methoxynaphthalene

Base Information

• Chemical Name: 1-Iodo-2-methoxynaphthalene
• CAS No.: 32721-21-4
• Molecular Formula: C11H9IO
• Molecular Weight: 284.096
• Hs Code.: 2909309090
• European Community (EC) Number: 848-468-2
• NSC Number: 110657
• DSSTox Substance ID: DTXSID90296637
• Nikkaji Number: J673.635A
• Wikidata: Q72483793
• Mol file: 32721-21-4.mol

Synonyms:1-iodo-2-methoxynaphthalene;32721-21-4;1-Iodo-2-methoxy-naphthalene;NSC110657;methoxy-1-iodonaphthalene;SCHEMBL1931431;1-iodanyl-2-methoxy-naphthalene;Naphthalene, 1-iodo-2-methoxy-;DTXSID90296637;AKOS002182300;NSC 110657;NSC-110657;AM20040177;CS-0191576;FT-0655263;EN300-2008988;A821388;A821504;SR-01000312973;SR-01000312973-1;Z1269120774

Chemical Property of 1-Iodo-2-methoxynaphthalene

Chemical Property:

• Vapor Pressure: 0.000103mmHg at 25°C
• Melting Point: 88 °C
• Refractive Index: 1.674
• Boiling Point: 348.1 °C at 760 mmHg
• Flash Point: 164.3 °C
• PSA: 9.23000
• Density: 1.674 g/cm³
• LogP: 3.45300
• Storage Temp.: 2-8°C
• XLogP3: 3.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 283.96981
• Heavy Atom Count: 13
• Complexity: 172

Purity/Quality:

99% ^*data from raw suppliers

1-Iodo-2-methoxynaphthalene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C2=CC=CC=C2C=C1)I

Technology Process of 1-Iodo-2-methoxynaphthalene

There total 3 articles about 1-Iodo-2-methoxynaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 18.0%

2-Methoxynaphthalene (93-04-9) + acetophenone (98-86-2) → 1-iodo-2-methoxynapthalene (32721-21-4) + (2-methoxy-[1]naphthyl)-phenyl-ethanedione

Guidance literature:

With iodine; dimethyl sulfoxide; at 100 ℃; for 48h;

DOI:10.1021/ol5004093

Reference yield:

2-Methoxynaphthalene (93-04-9) → 1-iodo-2-methoxynapthalene (32721-21-4) + 3-iodo-2-methoxynaphthalene (795278-91-0)

Guidance literature:

With iodine; ferric nitrate; phosphotungstic acid; In dichloromethane; at 20 ℃; for 6h;

DOI:10.1139/v05-187

Reference yield:

→ 1-iodo-2-methoxynapthalene (32721-21-4) + 1-chloro-2-methoxynaphthalene (13101-92-3)

Guidance literature:

upstream raw materials:

2-Methoxynaphthalene

acetophenone

Downstream raw materials:

(+/-)-2-methoxy-1-(2'-nitrophenyl)naphthalene

6,6'-dimethoxybiphenyl-3,3'-dicarboxylic acid

4-methoxy-3-(2-methoxy-[1]naphthyl)-benzoic acid

2-Methoxynaphthalene

Refernces

• 1、 Naka, Hiroshi,Uchiyama, Masanobu,Matsumoto, Yotaro,Wheatley, Andrew E. H.,McPartlin, Mary,Morey, James V.,Kondo, Yoshinori. "An aluminum ate base: Its design, structure, function, and reaction mechanism". . p. 1921 - 1930. Retrieved 2007/10/03.
• 2、 -. "2-(6'-methoxynaphth-2'yl) propionaldoxime and 5'-halo derivatives thereof". . . Retrieved 2008/06/13.