NSC30185

Base Information

• Chemical Name: NSC30185
• CAS No.: 3237-31-8
• Molecular Formula: C12H17 N O2 S
• Molecular Weight: 239.338
• Mol file: 3237-31-8.mol

Synonyms:N-Cyclohexylbenzenesulfonamide;NSC 30185

Chemical Property of NSC30185

Chemical Property:

• Vapor Pressure: 8.22E-06mmHg at 25°C
• Boiling Point: 374.7°Cat760mmHg
• Flash Point: 180.4°C
• Density: 1.2g/cm³

Purity/Quality:

99% ^*data from raw suppliers

N-CYCLOHEXYLBENZENESULFONAMIDE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of NSC30185

There total 21 articles about NSC30185 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

cyclohexylamine (108-91-8,157973-60-9) + benzenesulfonyl chloride (98-09-9) → N-cyclohexylbenzenesulfonamide (3237-31-8)

Guidance literature:

With picoline; In dichloromethane; at 20 ℃; for 1h;

DOI:10.1016/j.tetlet.2006.08.036

Reference yield: 96.0%

benzenesulfonamide (98-10-2) + cyclohexene (110-83-8) → N-cyclohexylbenzenesulfonamide (3237-31-8)

Guidance literature:

With boron trifluoride diethyl etherate; In 1,2-dichloro-ethane; at 60 ℃; for 24h; Sealed tube;

DOI:10.1039/c5ra10513g

Reference yield: 96.0%

benzenesulfonamide (98-10-2) + cyclohexane (110-82-7,25012-93-5) → N-cyclohexylbenzenesulfonamide (3237-31-8)

Guidance literature:

With 1,10-Phenanthroline; copper(I) bromide dimethylsulfide complex; di-tert-butyl peroxide; In tert-butyl alcohol; at 135 ℃; for 15h; Schlenk technique;

DOI:10.1002/cssc.201700783

upstream raw materials:

cyclohexylamine

benzenesulfonyl chloride

2-benzenesulfonyl-4,5-dichloropyridazin-3-one

benzenesulfonamide

Downstream raw materials:

N-Chlor-N-benzolsulfonyl-cyclohexylamin

N-Cyclohexyl-N-(benzolsulfenyl)benzolsulfonamid

2,2'-diselenobis(N-cyclohexyl benzenesulfonamide)

N-Cyclohexyl-N,N-di(benzol)sulfonimid

Refernces

• 1、 -. "AEROBIC OXIDATIVE SYNTHESIS OF SULFONAMIDE USING Cu CATALYST". Paragraph 0033-0037; 0039-0054; 0116-0117. . Retrieved 2021/04/06.
• 2、 Bourne, Richard A.,Kapur, Nikil,Nicholls, Thomas P.,Schotten, Christiane,Stephen, Hamish R.,Willans, Charlotte E.,Woodward, Madeleine. "A Versatile Electrochemical Batch Reactor for Synthetic Organic and Inorganic Transformations and Analytical Electrochemistry". . p. 1084 - 1089. Retrieved 2020/07/06.