acide dibromo-2,3 pentanoique

Base Information

• Chemical Name: acide dibromo-2,3 pentanoique
• CAS No.: 79912-57-5
• Molecular Formula: C₅H₈Br₂O₂
• Molecular Weight: 259.925
• Mol file: 79912-57-5.mol

Synonyms:acide dibromo-2,3 pentanoique

Chemical Property of acide dibromo-2,3 pentanoique

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of acide dibromo-2,3 pentanoique

There total 1 articles about acide dibromo-2,3 pentanoique which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

trans-2-pentenoic acid (13991-37-2) → (2R*,3S*)-2,3-dibromopentanoic acid (79912-57-5,139185-84-5)

Guidance literature:

With bromine; In dichloromethane; for 5h; Ambient temperature;

DOI:10.1055/s-1991-28403

Reference yield: 87.0%

(2R*,3S*)-2,3-dibromopentanoic acid (79912-57-5,139185-84-5) → (Z)-1-bromo-1-butene (31849-78-2)

Guidance literature:

With sodium hydrogencarbonate; In N,N-dimethyl-formamide; at 70 ℃; for 1h; under 97.5098 Torr; optical yield given as %de;

DOI:10.1021/ja204027a

Reference yield:

acide dibromo-2,3 pentanoique (79912-57-5) → (E)/(Z)-1-bromo-1-butene (31844-98-1) + 2-bromo-pent-2-enoic acid (98021-78-4)

Guidance literature:

With pyridine;

upstream raw materials:

trans-2-pentenoic acid

Downstream raw materials:

(E)/(Z)-1-bromo-1-butene

2-bromo-pent-2-enoic acid

(Z)-1-bromo-1-butene

Z-1-bromobutene

Refernces

• 1、 Hickmann, Volker,Kondoh, Azusa,Gabor, Barbara,Alcarazo, Manuel,Fuerstner, Alois. "Catalysis-based and protecting-group-free total syntheses of the marine oxylipins hybridalactone and the ecklonialactones A, B, and C". supporting information; experimental part. p. 13471 - 13480. Retrieved 2011/10/10.