3-fluorobenzenesulfonohydrazide

Base Information

• Chemical Name: 3-fluorobenzenesulfonohydrazide
• CAS No.: 890522-63-1
• Molecular Formula: C₆H₇FN₂O₂S
• Molecular Weight: 190.198
• Mol file: 890522-63-1.mol

Synonyms:3-fluorobenzenesulfonohydrazide

Chemical Property of 3-fluorobenzenesulfonohydrazide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-fluorobenzenesulfonohydrazide

There total 1 articles about 3-fluorobenzenesulfonohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-fluorobenzene-1-sulfonyl chloride (701-27-9) → 3-fluorobenzenesulfonohydrazide (890522-63-1)

Guidance literature:

With hydrazine hydrate; In tetrahydrofuran; at 20 ℃;

DOI:10.1039/C6OB01929C

Reference yield: 95.0%

N,N-dimethyl-2-(4-methylphenylethynyl)aniline (54655-09-3) + 3-fluorobenzenesulfonohydrazide (890522-63-1) → 3-((3-fluorophenyl)thio)-1-methyl-2-(p-tolyl)-1H-indole

Guidance literature:

With iodine; In ethyl acetate; at 80 ℃; for 2h; Green chemistry;

DOI:10.1039/c7ob00366h

Reference yield: 94.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + 3-fluorobenzenesulfonohydrazide (890522-63-1) → (E)-1-fluoro-3-(styrylsulfonyl)benzene

Guidance literature:

With tert.-butylhydroperoxide; iodine; sodium carbonate; In toluene; at 90 ℃; for 3h; stereoselective reaction; Inert atmosphere;

DOI:10.1016/j.tetlet.2018.02.078

upstream raw materials:

3-fluorobenzene-1-sulfonyl chloride

Downstream raw materials:

1,3,7-trimethyl-8-(m-fluorophenyl)-xanthine

3-(((3-fluorophenyl)sulfonyl)methyl)-1,3-dimethylindolin-2-one

3-(3-fluorophenyl)indolizine-1-carbonitrile

Refernces

• 1、 Zhang, Guofu,Fan, Qiankun,Zhao, Yiyong,Wang, Huimin,Ding, Chengrong. "Dual Roles of Rongalite: Reductive Coupling Reaction to Construct Thiosulfonates Using Sulfonyl Hydrazides". supporting information. p. 81 - 85. Retrieved 2020/11/03.
• 2、 Jiang, Huanfeng,Yan, Wuxin,Huang, Jiuzhong,Tan, Chaowei,Zhan, Lingzhi,Wu, Wanqing. "Palladium-Catalyzed Regio- and Stereoselective Sulfonylation of Aryl Propiolates with Sulfonyl Hydrazides: Access to (E)-β-Aryl Sulfonyl Acrylates". supporting information. p. 4575 - 4580. Retrieved 2019/09/16.