1,3-Dioxolane, 2-(2,2,2-trifluoroethyl)-

Base Information

• Chemical Name: 1,3-Dioxolane, 2-(2,2,2-trifluoroethyl)-
• CAS No.: 117971-08-1
• Molecular Formula: C₅H₇F₃O₂
• Molecular Weight: 156.105
• Mol file: 117971-08-1.mol

Synonyms:1,3-Dioxolane, 2-(2,2,2-trifluoroethyl)-

Chemical Property of 1,3-Dioxolane, 2-(2,2,2-trifluoroethyl)-

Chemical Property:

• PSA: 18.46000
• LogP: 1.31170

Purity/Quality:

99%min ^*data from raw suppliers

2-(2,2,2-Trifluoroethyl)-1,3-dioxolane 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,3-Dioxolane, 2-(2,2,2-trifluoroethyl)-

There total 3 articles about 1,3-Dioxolane, 2-(2,2,2-trifluoroethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.0%

1,1,1-trifluoropropylene (677-21-4) + ethylene glycol (107-21-1) → 2-(2,2,2-trifluoroethyl)-1,3-dioxolane (117971-08-1)

Guidance literature:

With palladium on activated charcoal; oxygen; copper dichloride; at 120 ℃; for 8h; under 7500.75 Torr;

DOI:10.1039/c6ra03208g

Reference yield:

3,3,3-trifluoroprop-1-yne (661-54-1) + ethylene glycol (107-21-1) → C5H7F3O2 + 2-(2,2,2-trifluoroethyl)-1,3-dioxolane (117971-08-1)

Guidance literature:

With potassium hydroxide; at 40 ℃; for 78h; under 4800.48 - 7500.75 Torr; Pressure; Inert atmosphere; Sealed tube;

Reference yield:

3,3,3-trifluoroprop-1-yne (661-54-1) + ethylene glycol (107-21-1) → 2-(2,2,2-trifluoroethyl)-1,3-dioxolane (117971-08-1) + 2-(3,3,3-trifluoro-1Z-propenyloxy)ethanol (117971-07-0)

Guidance literature:

With potassium hydroxide; at 80 ℃; for 5h; Title compound not separated from byproducts;

upstream raw materials:

3,3,3-trifluoroprop-1-yne

ethylene glycol

1,1,1-trifluoropropylene

Refernces

• 1、 Kang, Jian-Ping,Lu, Ju-You,Li, Yang,Wang, Zhi-Xuan,Mao, Wei,Lu, Jian. "Atom-economical synthesis of 3,3,3-trifluoropropanal dialkyl acetals through Pd/C catalyzed acetalization of 3,3,3-trifluoropropene". . p. 39387 - 39391. Retrieved 2016/06/01.