propane-2-sulfonic acid (2-(4-iodophenyl)propyl)amide

Base Information Edit

Chemical Name:propane-2-sulfonic acid (2-(4-iodophenyl)propyl)amide
CAS No.:375345-98-5
Molecular Formula:C₁₂H₁₈INO₂S
Molecular Weight:367.251
Hs Code.:
DSSTox Substance ID:DTXSID20457431
Wikidata:Q82280274
Mol file:375345-98-5.mol

Synonyms:propane-2-sulfonic acid (2-(4-iodophenyl)propyl)amide

Suppliers and Price of propane-2-sulfonic acid (2-(4-iodophenyl)propyl)amide

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of propane-2-sulfonic acid (2-(4-iodophenyl)propyl)amide Edit

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:367.01030
Heavy Atom Count:17
Complexity:316

Purity/Quality:: 99%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)S(=O)(=O)NCC(C)C1=CC=C(C=C1)I
Isomeric SMILES:C[C@@H](CNS(=O)(=O)C(C)C)C1=CC=C(C=C1)I

Technology Process of propane-2-sulfonic acid (2-(4-iodophenyl)propyl)amide

There total 11 articles about propane-2-sulfonic acid (2-(4-iodophenyl)propyl)amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 375345-97-4
propane-2-sulfonic acid (2-phenylpropyl)amide

: 375345-98-5
propane-2-sulfonic acid (2-(4-iodophenyl)propyl)amide

Guidance literature:: With sulfuric acid; iodine; acetic acid; periodic acid; In water; at 5 ℃;
DOI:10.1016/j.bmcl.2010.11.098

Reference yield:

: N-(2-(4-iodophenyl)allyl)propane-2-sulfonamide

: 375345-98-5
propane-2-sulfonic acid (2-(4-iodophenyl)propyl)amide

: 400629-27-8
N-(2-(4-iodophenyl)propyl)propane-2-sulfonamide

Guidance literature:: With 1,5-cyclooctadiene{[dibenzyl((4S,5S)-5-methyl-2-phenyl-4,5-dihydro-4-oxazolyl)methyl]dicyclohexylphosphinite κN:κP}iridium(I) tetrakis(3,5-bis(trifluoromethyl)phenyl)borate; hydrogen; In 1,2-dichloro-ethane; at 20 ℃; under 750.075 Torr; Overall yield = 93 percent; Overall yield = 60 mg; enantioselective reaction; Sealed tube;
DOI:10.1002/adsc.201900748

Reference yield:

: 1823-91-2
1-phenylethyl cyanide

: 375345-98-5
propane-2-sulfonic acid (2-(4-iodophenyl)propyl)amide

Guidance literature:: Multi-step reaction with 4 steps

1.1: hydrogenchloride; ethanol; hydrogen / water-wet 5% palladium on carbon / water / 3 h / 50 - 64 °C / 3878.71 - 4033.86 Torr / Under nitrogen

2.1: sodium hydroxide; ethanol / 1.6 h / Under nitrogen

3.1: dmap; triethylamine / hexane; dichloromethane / 3 h / 5 - 20 °C

4.1: sulfuric acid; acetic acid / water

4.2: 3 h / 60 °C

With hydrogenchloride; dmap; sodium hydroxide; ethanol; sulfuric acid; hydrogen; acetic acid; triethylamine; water-wet 5% palladium on carbon; In hexane; dichloromethane; water;