2-chloro-5-nitro-3-ethylbenzene

Base Information

• Chemical Name: 2-chloro-5-nitro-3-ethylbenzene
• CAS No.: 49709-31-1
• Molecular Formula: C₈H₈ClNO₂
• Molecular Weight: 185.61
• Mol file: 49709-31-1.mol

Synonyms:2-chloro-5-nitro-3-ethylbenzene

Chemical Property of 2-chloro-5-nitro-3-ethylbenzene

Chemical Property:

• Melting Point: 86-87 °C
• Boiling Point: 263-265 °C(Press: 730 Torr)
• Density: 1.270±0.06 g/cm3(Predicted)

Purity/Quality:

98.5% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-chloro-5-nitro-3-ethylbenzene

There total 6 articles about 2-chloro-5-nitro-3-ethylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-amino-3-ethyl-1-nitrobenzene (6853-29-8) → 2-chloro-5-nitro-3-ethylbenzene (49709-31-1)

Guidance literature:

With hydrogenchloride; sodium nitrite; Behandeln mit einer aus Kupfer(I)-chlorid und wss. Salzsaeure hergestellten Loesung;

DOI:10.1021/jo01365a012

Reference yield:

ortho-ethylaniline (578-54-1) → 2-chloro-5-nitro-3-ethylbenzene (49709-31-1)

Guidance literature:

Multi-step reaction with 3 steps

1: acetic acid

2: acetic acid; HNO₃ / folgenden Hydrolysieren des Reaktionsprodukts

3: aqueous hydrochloric acid; sodium nitrite / Behandeln mit einer aus Kupfer(I)-chlorid und wss. Salzsaeure hergestellten Loesung

With hydrogenchloride; nitric acid; acetic acid; sodium nitrite;

DOI:10.1021/jo01365a012

Reference yield:

2-acetamido-1-ethylbenzene (33098-65-6) → 2-chloro-5-nitro-3-ethylbenzene (49709-31-1)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid; HNO₃ / folgenden Hydrolysieren des Reaktionsprodukts

2: aqueous hydrochloric acid; sodium nitrite / Behandeln mit einer aus Kupfer(I)-chlorid und wss. Salzsaeure hergestellten Loesung

With hydrogenchloride; nitric acid; acetic acid; sodium nitrite;

DOI:10.1021/jo01365a012

upstream raw materials:

4-amino-3-ethyl-1-nitrobenzene

5-chloro-4-ethyl-2-nitroaniline

ortho-ethylaniline

2-acetamido-1-ethylbenzene

Downstream raw materials:

3-chloro-5-nitrobenzoic acid

2-ethyl-4-amino-thiophenol

2-ethyl-4-nitro-thiophenol

5-aminobenzo[b]thiophene