2,5-Dichloro-4-nitrosophenol

Base Information

• Chemical Name: 2,5-Dichloro-4-nitrosophenol
• CAS No.: 35421-04-6
• Molecular Formula: C₆H₃Cl₂NO₂
• Molecular Weight: 192.001
• DSSTox Substance ID: DTXSID701232279
• Mol file: 35421-04-6.mol

Synonyms:2,5-dichloro-4-nitrosophenol;35421-04-6;4-nitroso-2,5-dichlorophenol;SCHEMBL10875444;DTXSID701232279;STK693121;AKOS005605004;MCULE-9715846915;2,5-Dichloro-2,5-cyclohexadiene-1,4-dione 1-oxime

Chemical Property of 2,5-Dichloro-4-nitrosophenol

Chemical Property:

• XLogP3: 2.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 190.9540837
• Heavy Atom Count: 11
• Complexity: 156

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=C(C(=CC(=C1Cl)O)Cl)N=O

Technology Process of 2,5-Dichloro-4-nitrosophenol

There total 3 articles about 2,5-Dichloro-4-nitrosophenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Chloro-1,4-benzoquinone (695-99-8) → 2,5-dichloro-[1,4]benzoquinone monooxime (35421-04-6)

Guidance literature:

Multi-step reaction with 2 steps

1: concentrated hydrochloric acid / Oxydation des Reaktionsprodukts mit Kalium- oder Natriumdichromat und Schwefelsaeure

2: benzene; alcohol; hydroxylamine hydrochloride

With hydrogenchloride; ethanol; hydroxylamine hydrochloride; benzene;

Reference yield:

2,5-Dichloro-1,4-benzoquinone (615-93-0) → 2,5-dichloro-[1,4]benzoquinone monooxime (35421-04-6) + 2,5-dichloro-[1,4]benzoquinone dioxime

Guidance literature:

With ethanol; hydroxylamine hydrochloride;

Reference yield:

2,5-dichlorophenol (583-78-8) + cyclopentyl nitrite (67764-33-4) → 2,5-dichloro-[1,4]benzoquinone monooxime (35421-04-6)

Guidance literature:

With sulfuric acid;

DOI:10.1557/JMR.2000.0097

upstream raw materials:

2,5-Dichloro-1,4-benzoquinone

2,5-dichlorophenol

cyclopentyl nitrite

2-Chloro-1,4-benzoquinone

Downstream raw materials:

2,5-dichloro-4-nitrophenol