2-Amino-6-nitroquinoxaline

Base Information

• Chemical Name: 2-Amino-6-nitroquinoxaline
• CAS No.: 115726-26-6
• Molecular Formula: C₈H₆N₄O₂
• Molecular Weight: 190.161
• DSSTox Substance ID: DTXSID60376430
• Wikidata: Q82165362
• Mol file: 115726-26-6.mol

Synonyms:6-nitroquinoxalin-2-amine;115726-26-6;2-AMINO-6-NITROQUINOXALINE;2-Quinoxalinamine,6-nitro-;Chlorhydroxquinoline;DTXSID60376430;AKOS000248101;FT-0691552

Chemical Property of 2-Amino-6-nitroquinoxaline

Chemical Property:

• Vapor Pressure: 1.46E-06mmHg at 25°C
• Melting Point: 303-306 °C
• Refractive Index: 1.759
• Boiling Point: 398.6 °C at 760 mmHg
• PKA: 2.06±0.48(Predicted)
• Flash Point: 194.9 °C
• PSA: 97.62000
• Density: 1.532 g/cm³
• LogP: 2.22460
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 0
• Exact Mass: 190.04907545
• Heavy Atom Count: 14
• Complexity: 230

Purity/Quality:

98%Min ^*data from raw suppliers

2-AMINO-6-NITROQUINOXALINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=NC(=CN=C2C=C1[N+](=O)[O-])N

Technology Process of 2-Amino-6-nitroquinoxaline

There total 5 articles about 2-Amino-6-nitroquinoxaline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

2-Chloro-6-nitroquinoxaline (6272-25-9) → 2-amino-6-nitroquinoxaline (115726-26-6)

Guidance literature:

With ammonia; In methanol; at 130 ℃; for 8h;

Reference yield: 51.0%

6-nitroquinoxaline (6639-87-8) → 2-amino-6-nitroquinoxaline (115726-26-6) + 5-amino-6-nitroquinoxaline (57436-91-6)

Guidance literature:

With potassium permanganate; ammonia; at -33 ℃; for 5h;

Reference yield: 18.0%

2-bromo-6-nitroquinoxaline (142396-57-4) → 2-amino-6-nitroquinoxaline (115726-26-6) + 5-amino-2-bromo-6-nitroquinoxaline (142396-52-9)

Guidance literature:

With potassium permanganate; ammonia; at -33 ℃; for 5h;

upstream raw materials:

6-nitroquinoxaline

2-Chloro-6-nitroquinoxaline

2-bromo-6-nitroquinoxaline

2-hydroxy-6-nitroquinoxaline

Refernces