4-(methoxycarbonyl) phenyl propyl fumarate

Base Information

• Chemical Name: 4-(methoxycarbonyl) phenyl propyl fumarate
• CAS No.: 1584188-11-3
• Molecular Formula: C₁₅H₁₆O₆
• Molecular Weight: 292.288
• Mol file: 1584188-11-3.mol

Synonyms:4-(methoxycarbonyl) phenyl propyl fumarate

Chemical Property of 4-(methoxycarbonyl) phenyl propyl fumarate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(methoxycarbonyl) phenyl propyl fumarate

There total 2 articles about 4-(methoxycarbonyl) phenyl propyl fumarate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

propyl (E)-4-chloro-4-oxo-2-butenoate (26367-49-7) + methyl 4-hydroxylbenzoate (99-76-3,156291-94-0) → 4-(methoxycarbonyl) phenyl propyl fumarate (1584188-11-3)

Guidance literature:

With sodium hydride; In tetrahydrofuran; at 20 ℃;

DOI:10.1016/j.molstruc.2014.01.063

Reference yield:

Monopropyl maleate (925-03-1) → 4-(methoxycarbonyl) phenyl propyl fumarate (1584188-11-3)

Guidance literature:

Multi-step reaction with 3 steps

1: aluminum (III) chloride / 2 h / 70 °C

2: oxalyl dichloride / N,N-dimethyl-formamide; tetrahydrofuran / 2 h / 20 °C

3: sodium hydride / tetrahydrofuran / 20 °C

With aluminum (III) chloride; oxalyl dichloride; sodium hydride; In tetrahydrofuran; N,N-dimethyl-formamide;

DOI:10.1016/j.molstruc.2014.01.063

upstream raw materials:

Monopropyl maleate

propyl (E)-4-chloro-4-oxo-2-butenoate

methyl 4-hydroxylbenzoate

Refernces