N-SUCCINIMIDYL FERROCENECARBOXYLATE

Base Information

• Chemical Name: N-SUCCINIMIDYL FERROCENECARBOXYLATE
• CAS No.: 115223-09-1
• Molecular Formula: C15H13 Fe N O4
• Molecular Weight: 327.11
• Hs Code.: 29339900
• Mol file: 115223-09-1.mol

Synonyms:Ferrocenemonocarboxylic acid N-hydroxy succinimide ester

Chemical Property of N-SUCCINIMIDYL FERROCENECARBOXYLATE

Chemical Property:

• PSA: 63.68000
• LogP: 0.95580

Purity/Quality:

98%,99%, ^*data from raw suppliers

N-Succinimidyl Ferrocenecarboxylate >98.0%(HPLC) ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-SUCCINIMIDYL FERROCENECARBOXYLATE

There total 1 articles about N-SUCCINIMIDYL FERROCENECARBOXYLATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1-hydroxy-pyrrolidine-2,5-dione (6066-82-6) + ferrocenecarboxylic acid (1271-42-7) → ferrocene carboxylic acid N-hydroxysuccinimide ester (115223-09-1)

Guidance literature:

With dicyclohexyl-carbodiimide; In 1,4-dioxane; for 12h;

Reference yield: 15.0%

ferrocene carboxylic acid N-hydroxysuccinimide ester (115223-09-1) + t-butyl (RS)-phenylalaninate (16367-71-8) → (C5H5)Fe(C5H4)CONHCH(CH2C6H5)COOC(CH3)3

Guidance literature:

With sodium carbonate; In water; dropwise addn. of H-Phe-O(tBu) in 0.2 M Na2CO3 to suspn. of ferrocenylsuccinimidylcarboxylate in 0.2 M Na2CO3, stirred (1 h, room temp.), extn. with ethyl acetate; org. phase dried (MgSO4), conc. in vac., filtered (silica gel, ethyl acetate/ hexane (1:3)), ground with hexane; elem. anal.;

Reference yield:

ferrocene carboxylic acid N-hydroxysuccinimide ester (115223-09-1) + trans-1,4-diaminocyclohexane (3114-70-3) → C17H22FeN2O

Guidance literature:

With 1,4-diaza-bicyclo[2.2.2]octane; In dichloromethane; Cooling with ice;

upstream raw materials:

1-hydroxy-pyrrolidine-2,5-dione

ferrocenecarboxylic acid

Refernces

• 1、 Lai, Wenqiang,Tang, Dianping,Fu, Libing,Que, Xiaohua,Zhuang, Junyang,Chen, Guonan. "A squaric acid-stimulated electrocatalytic reaction for sensing biomolecules with cycling signal amplification". . p. 4761 - 4763. Retrieved 2013.
• 2、 Takada, Tadao,Tochi, Takaaki,Nakamura, Mitsunobu,Yamana, Kazushige. "Preparation of ferrocene-functionalized gold nanoparticles by primer extension reaction on the particle surface". . p. 2661 - 2663. Retrieved 2014.
• 3、 Debela,Thorimbert,Hasenknopf,O'Sullivan,Ortiz. "Electrochemical primer extension for the detection of single nucleotide polymorphisms in the cardiomyopathy associated MYH7 gene". . p. 757 - 759. Retrieved 2016.
• 4、 -. "Ferrocene amide compound modified gold nanoparticles as well as preparation method and application thereof". Paragraph 0048-0052. . Retrieved 2020/03/05.