Pyrazino[1,2-a]benzimidazole, 1,2,3,4-tetrahydro-2-methyl- (6CI)

Base Information

• Chemical Name: Pyrazino[1,2-a]benzimidazole, 1,2,3,4-tetrahydro-2-methyl- (6CI)
• CAS No.: 115213-55-3
• Molecular Formula: C₁₁H₁₃N₃
• Molecular Weight: 187.244
• Mol file: 115213-55-3.mol

Synonyms:Pyrazino[1,2-a]benzimidazole, 1,2,3,4-tetrahydro-2-methyl- (6CI);1,2,3,4-TETRAHYDRO-2-METHYL-PYRAZINO[1,2-A]BENZIMIDAZOLE

Chemical Property of Pyrazino[1,2-a]benzimidazole, 1,2,3,4-tetrahydro-2-methyl- (6CI)

Chemical Property:

• PSA: 21.06000
• LogP: 1.41960

Purity/Quality:

99%min ^*data from raw suppliers

2-Methyl-1,2,3,4-tetrahydrobenzo[4,5]imidazo[1,2-a]pyrazine 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Pyrazino[1,2-a]benzimidazole, 1,2,3,4-tetrahydro-2-methyl- (6CI)

There total 12 articles about Pyrazino[1,2-a]benzimidazole, 1,2,3,4-tetrahydro-2-methyl- (6CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-{2-[(benzyl-methyl-amino)-methyl]-benzimidazol-1-yl}-ethanol (101719-98-6) → 2-methyl-1,2,3,4-tetrahydro-benz[4,5]imidazo[1,2-a]pyrazine (115213-55-3)

Guidance literature:

Multi-step reaction with 2 steps

1: SOCl₂ / und anschliessenden Erwaermen in Isopropylalkohol

2: palladium/charcoal; methanol / Hydrogenation

With methanol; palladium on activated charcoal; thionyl chloride;

DOI:10.1002/hlca.19560390416

Reference yield:

2-benzyl-2-methyl-1,2,3,4-tetrahydro-benz[4,5]imidazo[1,2-a]pyrazinium; chloride (109569-51-9) → 2-methyl-1,2,3,4-tetrahydro-benz[4,5]imidazo[1,2-a]pyrazine (115213-55-3)

Guidance literature:

With methanol; palladium on activated charcoal; Hydrogenation;

DOI:10.1002/hlca.19560390416

Reference yield:

2-benzyl-2-methyl-1,2,3,4-tetrahydro-benz[4,5]imidazo[1,2-a]pyrazinium; bromide (109644-50-0) → 2-methyl-1,2,3,4-tetrahydro-benz[4,5]imidazo[1,2-a]pyrazine (115213-55-3)

Guidance literature:

With methanol; palladium on activated charcoal; Hydrogenation;

DOI:10.1002/hlca.19560390416

upstream raw materials:

NSC 700996

methyl iodide

2-benzyl-2-methyl-1,2,3,4-tetrahydro-benz[4,5]imidazo[1,2-a]pyrazinium; chloride

2-benzyl-2-methyl-1,2,3,4-tetrahydro-benz[4,5]imidazo[1,2-a]pyrazinium; bromide