C₁₀H₈Cl₂N₂O

Base Information

• Chemical Name: C₁₀H₈Cl₂N₂O
• CAS No.: 14575-33-8
• Molecular Formula: C₁₀H₈Cl₂N₂O
• Molecular Weight: 243.092
• Mol file: 14575-33-8.mol

Synonyms:C₁₀H₈Cl₂N₂O

Chemical Property of C₁₀H₈Cl₂N₂O

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₀H₈Cl₂N₂O

There total 2 articles about C₁₀H₈Cl₂N₂O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acetic acid-[N'-(2,4-dichloro-phenyl)-hydrazide] (14580-40-6) + ethyl acetoacetate (141-97-9) → C10H8Cl2N2O (14575-33-8)

Guidance literature:

With phosphorus trichloride; at 50 ℃; regioselective reaction;

DOI:10.1021/jm3007323

Reference yield:

acetic acid-[N'-(2,4-dichloro-phenyl)-hydrazide] (14580-40-6) + ethyl acetoacetate (141-97-9) → 1-(2,4-dichloro-phenyl)-5-methyl-1,2-dihydro-pyrazol-3-one (14575-33-8)

Guidance literature:

With phosphorus trichloride;

DOI:10.1039/jr9310000786

Reference yield:

N-(2-chlorethyl)morpholine (3240-94-6) + C10H8Cl2N2O (14575-33-8) → C16H19Cl2N3O2 (1392758-97-2)

Guidance literature:

C₁₀H₈Cl₂N₂O; With potassium carbonate; In N,N-dimethyl-formamide; at 0 - 20 ℃; Alkaline conditions; Inert atmosphere;

N-(2-chlorethyl)morpholine; In N,N-dimethyl-formamide; Inert atmosphere; Heating; Alkaline conditions;

DOI:10.1021/jm3007323

upstream raw materials:

acetic acid-[N'-(2,4-dichloro-phenyl)-hydrazide]

ethyl acetoacetate

Downstream raw materials:

C₁₆H₁₉Cl₂N₃O₂

Refernces