2-[(2-AMINOPHENYL)THIO]BENZOIC ACID HYDROCHLORIDE

Base Information

• Chemical Name: 2-[(2-AMINOPHENYL)THIO]BENZOIC ACID HYDROCHLORIDE
• CAS No.: 114724-41-3
• Molecular Formula: C₁₃H₁₁NO₂S*ClH
• Molecular Weight: 281.763
• Mol file: 114724-41-3.mol

Synonyms:Benzoicacid, 2-[(2-aminophenyl)thio]-, hydrochloride (9CI);2-(2-Aminophenylthio)benzoic acid hydrochloride

Chemical Property of 2-[(2-AMINOPHENYL)THIO]BENZOIC ACID HYDROCHLORIDE

Chemical Property:

• Vapor Pressure: 1.84E-08mmHg at 25°C
• Boiling Point: 438.5°C at 760 mmHg
• Flash Point: 219°C
• PSA: 88.62000
• LogP: 4.50140

Purity/Quality:

98%min ^*data from raw suppliers

2-(2-Aminophenylthio)benzoicAcidHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2-(2-Aminophenylthio)benzoic Acid Hydrochloride is a compound used in the preparation of cyclic sulfonium ylides.

Technology Process of 2-[(2-AMINOPHENYL)THIO]BENZOIC ACID HYDROCHLORIDE

There total 1 articles about 2-[(2-AMINOPHENYL)THIO]BENZOIC ACID HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2?(2?nitrophenylsulfanyl)benzoic acid (19806-43-0) → 2-(2-aminophenylthio)benzoic acid hydrochloride (114724-41-3)

Guidance literature:

2?(2?nitrophenylsulfanyl)benzoic acid; With hydrogen; nickel; In water; at 110 ℃; for 3h; under 23272.3 Torr;

With hydrogenchloride; In water;

Reference yield:

2-(2-aminophenylthio)benzoic acid hydrochloride (114724-41-3) → dibenzo[b,f][1,4]thiazepin-11-one (3159-07-7)

Guidance literature:

Multi-step reaction with 2 steps

1: dioxane / 18 h / Ambient temperature

2: 55 percent / trifluoroacetic anhydride / dimethylformamide / 1.) reflux, 1 h, 2.) RT, overnight

With trifluoroacetic anhydride; In 1,4-dioxane; N,N-dimethyl-formamide;

Reference yield:

2-(2-aminophenylthio)benzoic acid hydrochloride (114724-41-3) → 2-(2-trifluoroacetylaminophenylsulfinyl)benzoic acid

Guidance literature:

Multi-step reaction with 2 steps

1: dioxane / 18 h / Ambient temperature

2: 74 percent / tert-butyl hypochlorite / CH₂Cl₂; trifluoroacetic acid; H₂O

With tert-butylhypochlorite; In 1,4-dioxane; dichloromethane; water; trifluoroacetic acid;

upstream raw materials:

2?(2?nitrophenylsulfanyl)benzoic acid

Downstream raw materials:

2-(2-trifluoroacetylaminophenylthio)benzoic acid

2-(2-acetylaminophenylthio)benzoic acid

dibenzo[b,f][1,4]thiazepin-11-one

11-piperazin-1-yldibenzo[b,f][1,4]thiazepine hydrochloride

Refernces