β-N-(α-phenylethyl)amino-β-trifluoromethylacrylic acid

Base Information

• Chemical Name: β-N-(α-phenylethyl)amino-β-trifluoromethylacrylic acid
• CAS No.: 128404-38-6
• Molecular Formula: C₁₃H₁₄F₃NO₂
• Molecular Weight: 273.255
• Mol file: 128404-38-6.mol

Synonyms:β-N-(α-phenylethyl)amino-β-trifluoromethylacrylic acid

Chemical Property of β-N-(α-phenylethyl)amino-β-trifluoromethylacrylic acid

Chemical Property:

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Technology Process of β-N-(α-phenylethyl)amino-β-trifluoromethylacrylic acid

There total 1 articles about β-N-(α-phenylethyl)amino-β-trifluoromethylacrylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

methyl 4,4,4-trifluoroacetoacetate (83643-84-9,488711-09-7) + (S)-1-phenyl-ethylamine (2627-86-3) → β-N-(α-phenylethyl)amino-β-trifluoromethylacrylic acid (128404-38-6)

Guidance literature:

With toluene-4-sulfonic acid; In toluene; Heating;

upstream raw materials:

methyl 4,4,4-trifluoroacetoacetate

(S)-1-phenyl-ethylamine

Refernces