2-Thiazolemethanol, -alpha--ethenyl-

Base Information

• Chemical Name: 2-Thiazolemethanol, -alpha--ethenyl-
• CAS No.: 112969-95-6
• Molecular Formula: C₆H₇NOS
• Molecular Weight: 141.194
• Mol file: 112969-95-6.mol

Synonyms:2-Thiazolemethanol, -alpha--ethenyl-

Chemical Property of 2-Thiazolemethanol, -alpha--ethenyl-

Chemical Property:

• Boiling Point: 217.5±33.0 °C(Predicted)
• PKA: 12.12±0.20(Predicted)
• PSA: 61.36000
• Density: 1.229±0.06 g/cm3(Predicted)
• LogP: 1.36250

Purity/Quality:

99%min ^*data from raw suppliers

a-ethenyl-2-Thiazolemethanol 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Thiazolemethanol, -alpha--ethenyl-

There total 1 articles about 2-Thiazolemethanol, -alpha--ethenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(α-trimethylsiloxy)-allylthiazole (87636-29-1) → 1-(thiazol-2-yl)-prop-2-en-1-ol (112969-95-6)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; for 1h; Yield given;

DOI:10.1021/jo00243a029

Reference yield: 64.0%

1-(thiazol-2-yl)-prop-2-en-1-ol (112969-95-6) → 2-propionylthiazole (43039-98-1)

Guidance literature:

With sodium hydride; In tetrahydrofuran; at 0 - 20 ℃; for 9h; Inert atmosphere;

DOI:10.1016/j.tet.2011.03.052

upstream raw materials:

2-(α-trimethylsiloxy)-allylthiazole

Downstream raw materials:

2-propionylthiazole

Refernces