1,3-DIMETHYL-6-FLUOROTHYMINE

Base Information

• Chemical Name: 1,3-DIMETHYL-6-FLUOROTHYMINE
• CAS No.: 112706-71-5
• Molecular Formula: C₇H₉FN₂O₂
• Molecular Weight: 172.159
• Mol file: 112706-71-5.mol

Synonyms:1,3-Dimethyl-6-fluorothymine

Chemical Property of 1,3-DIMETHYL-6-FLUOROTHYMINE

Chemical Property:

• Vapor Pressure: 0.361mmHg at 25°C
• Refractive Index: 1.519
• Boiling Point: 198.4°Cat760mmHg
• PKA: -3.72±0.60(Predicted)
• Flash Point: 73.8°C
• PSA: 44.00000
• Density: 1.3g/cm³
• LogP: -0.46850

Purity/Quality:

99%min ^*data from raw suppliers

1,3-DIMETHYL-6-FLUOROTHYMINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,3-DIMETHYL-6-FLUOROTHYMINE

There total 2 articles about 1,3-DIMETHYL-6-FLUOROTHYMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dimethyl sulfate (77-78-1) + 6-fluorothymine (31458-36-3) → 1,3-dimethyl-6-fluorothymine (112706-71-5)

Guidance literature:

With alkali; In water; at 20 - 25 ℃; for 2h;

DOI:10.1016/0584-8539(90)80105-8

Reference yield:

2,4,6-trifluoro-5-methylpyrimidine (18260-60-1) → 1,3-dimethyl-6-fluorothymine (112706-71-5)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrolysis

2: alkali / H₂O / 2 h / 20 - 25 °C

With alkali; In water;

DOI:10.1016/0584-8539(90)80105-8

upstream raw materials:

dimethyl sulfate

6-fluorothymine

2,4,6-trifluoro-5-methylpyrimidine

Refernces