3'-iodo-4'-azidopropiophenone

Base Information

• Chemical Name: 3'-iodo-4'-azidopropiophenone
• CAS No.: 1354635-88-3
• Molecular Formula: C₉H₈IN₃O
• Molecular Weight: 301.087
• Mol file: 1354635-88-3.mol

Synonyms:3'-iodo-4'-azidopropiophenone

Chemical Property of 3'-iodo-4'-azidopropiophenone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 3'-iodo-4'-azidopropiophenone

There total 1 articles about 3'-iodo-4'-azidopropiophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3'-iodo-4'-aminopropiophenone (942035-58-7) → 3'-iodo-4'-azidopropiophenone (1354635-88-3)

Guidance literature:

3'-iodo-4'-aminopropiophenone; With trifluoroacetic acid; sodium nitrite; at 0 ℃; for 0.75h; Darkness;

With sodium azide; In diethyl ether; at 0 ℃; for 1h; Darkness;

DOI:10.1016/j.bmcl.2011.10.086

Reference yield:

3'-iodo-4'-azidopropiophenone (1354635-88-3) → C9H7BrIN3O

Guidance literature:

With bromine; In chloroform; at 50 ℃; for 20h;

DOI:10.1016/j.bmcl.2011.10.086

Reference yield:

3'-iodo-4'-azidopropiophenone (1354635-88-3) → [125I]-SADU-3-72 (1354635-87-2)

Guidance literature:

Multi-step reaction with 2 steps

1: bromine / chloroform / 20 h / 50 °C

2: 1-methyl-pyrrolidin-2-one / 0.17 h / 55 °C

With 1-methyl-pyrrolidin-2-one; bromine; In chloroform;

DOI:10.1016/j.bmcl.2011.10.086

upstream raw materials:

3'-iodo-4'-aminopropiophenone

Downstream raw materials:

[125I]-SADU-3-72

Refernces