2-(Acetoxymethoxy)-1,3-propanediyl Dibenzoate

Base Information

• Chemical Name: 2-(Acetoxymethoxy)-1,3-propanediyl Dibenzoate
• CAS No.: 110874-22-1
• Molecular Formula: C20H20 O7
• Molecular Weight: 372.375
• Mol file: 110874-22-1.mol

Synonyms:1,3-Propanediol,2-[(acetyloxy)methoxy]-, dibenzoate (9CI);2-Acetoxymethoxy-1,3-dibenzoyloxypropane

Chemical Property of 2-(Acetoxymethoxy)-1,3-propanediyl Dibenzoate

Chemical Property:

• Boiling Point: 476.6±40.0 °C(Predicted)
• PSA: 88.13000
• Density: 1.231±0.06 g/cm3(Predicted)
• LogP: 2.60620
• Storage Temp.: Refrigerator
• Solubility.: Chloroform (Slightly), Methanol (Slightly)

Purity/Quality:

98%Min ^*data from raw suppliers

2-(Acetoxymethoxy)-1,3-propanediylDibenzoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(Acetoxymethoxy)-1,3-propanediyl Dibenzoate

There total 3 articles about 2-(Acetoxymethoxy)-1,3-propanediyl Dibenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

acetic anhydride (108-24-7) + 2-(methoxymethoxy)-1,3-propanediyl dibenzoate (110874-21-0) → 2-(acetoxymethoxy)-1,3-propanediyl dibenzoate (110874-22-1)

Guidance literature:

With boron trifluoride diethyl etherate; at 0 ℃; for 2h;

DOI:10.1021/jm00396a021

Reference yield:

1,3-dichloro-2-(methoxymethoxy)propane (70905-45-2) → 2-(acetoxymethoxy)-1,3-propanediyl dibenzoate (110874-22-1)

Guidance literature:

Multi-step reaction with 2 steps

2: H₂SO₄

With sulfuric acid;

DOI:10.1080/15257779508009494

Reference yield:

acetic acid (64-19-7,77671-22-8) + 2-(methoxymethoxy)-1,3-propanediyl dibenzoate (110874-21-0) → 2-(acetoxymethoxy)-1,3-propanediyl dibenzoate (110874-22-1)

Guidance literature:

acetic acid; 2-(methoxymethoxy)-1,3-propanediyl dibenzoate; With boron trifluoride diethyl etherate; at 20 ℃; for 1h;

With water; sodium carbonate;

upstream raw materials:

acetic anhydride

2-(methoxymethoxy)-1,3-propanediyl dibenzoate

1,3-dichloro-2-(methoxymethoxy)propane

acetic acid

Downstream raw materials:

2-<(4-amino-1,2-dihydro-2-oxo-1-pyrimidinyl)methyloxy>-1,3-propanediyl dibenzoate

2-((5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methoxy)propane-1,3-diyl dibenzoate

C₂₃H₂₁N₅O₅

C₂₃H₂₁N₅O₆

Refernces

• 1、 -. "METHOD FOR PRODUCING 2-NITROIMIDAZOLE DERIVATIVE". Page/Page column 7. . Retrieved 2009/12/23.
• 2、 Beauchamp, Lilia M.,Serling, Barbara L.,Kelsey, John E.,Biron, Karen K.,Collins, Peter,et al.. "Effect of Acyclic Pyrimidines Related to 9-guanine on Herpesviruses". . p. 144 - 149. Retrieved 2007/10/02.