(±)-2-benzyl-1-octanol

Base Information

• Chemical Name: (±)-2-benzyl-1-octanol
• CAS No.: 107613-28-5
• Molecular Formula: C₁₅H₂₄O
• Molecular Weight: 220.355
• Mol file: 107613-28-5.mol

Synonyms:(±)-2-benzyl-1-octanol

Chemical Property of (±)-2-benzyl-1-octanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (±)-2-benzyl-1-octanol

There total 13 articles about (±)-2-benzyl-1-octanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

α-hexylcinnamaldehyde (101-86-0) → (±)-2-benzyl-1-octanol (107613-28-5)

Guidance literature:

With sodium tetrahydroborate; palladium diacetate; In methanol; at 20 ℃; for 1h;

DOI:10.1080/00397910902788117

Reference yield: 91.0%

α-hexylcinnamaldehyde (101-86-0) → (±)-2-benzyl-1-octanol (107613-28-5) + trans-α-n-hexylcinnamic alcohol (53892-67-4)

Guidance literature:

With chlorine[2-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxypyridine](pentamethylcyclopentadienyl)iridium(III) chloride; sodium formate; In water; at 80 ℃; for 0.5h; chemoselective reaction; Schlenk technique;

DOI:10.1021/acs.organomet.9b00353

Reference yield: 72.0%

octanol (111-87-5) + benzyl alcohol (100-51-6,185532-71-2) → (±)-2-benzyl-1-octanol (107613-28-5)

Guidance literature:

With potassium tert-butylate; In 1,4-dioxane; at 150 ℃; for 24h; Inert atmosphere;

DOI:10.1039/d1ob00045d

upstream raw materials:

Octanal

benzyl alcohol

(2E)-3-phenyl-2-propen-1-ol

α-hexylcinnamaldehyde

Downstream raw materials:

C₁₂H₂₂O₄

(±)-dihydro-4-hexyl-2(3H)-furanone

Refernces

• 1、 Utsunomiya, Masayoshi,Kondo, Ryota,Oshima, Toshinori,Safumi, Masatoshi,Suzuki, Takeyuki,Obora, Yasushi. "Cross β-arylmethylation of alcohols catalysed by recyclable Ti-Pd alloys not requiring pre-activation". supporting information. p. 5139 - 5142. Retrieved 2021/05/31.
• 2、 Luo, Nianhua,Liao, Jianhua,Ouyang, Lu,Wen, Huiling,Liu, Jitian,Tang, Weiping,Luo, Renshi. "Highly pH-Dependent Chemoselective Transfer Hydrogenation of α,β-Unsaturated Aldehydes in Water". . p. 3025 - 3031. Retrieved 2019/08/30.