Technology Process of 5-bromo-2,3-dimethoxybenzoic acid chloride
There total 11 articles about 5-bromo-2,3-dimethoxybenzoic acid chloride which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
thionyl chloride; N,N-dimethyl-formamide;
In
toluene;
at 65 ℃;
for 1h;
DOI:10.1021/jm00170a040
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1) 99percent hydrazine hydrate, 2) KOH / 1) reflux, 2) reflux
2: 51 percent / KMnO4 / H2O / 10 h / Heating
3: SOCl2 / 2 h / Heating
With
potassium hydroxide; potassium permanganate; thionyl chloride; hydrazine hydrate;
In
water;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 93 percent / K2CO3 / butan-2-one / 2 h / 80 °C
2: 72 percent / KMnO4; K2HPO4*3H2O / 2-methyl-propan-2-ol; H2O / 0.5 h
3: SOCl2; DMF / toluene / 2 h / 80 °C
With
potassium permanganate; dipotassium hydrogenphosphate; thionyl chloride; potassium carbonate; N,N-dimethyl-formamide;
In
water; toluene; butanone; tert-butyl alcohol;
1: Methylation / 2: Oxidation / 3: Substitution;
DOI:10.1002/(SICI)1099-1344(20000330)43:4<331::AID-JLCR320>3.0.CO;2-H
