3,3'-Dibromo-4,4'-dimethoxybiphenyl

Base Information

• Chemical Name: 3,3'-Dibromo-4,4'-dimethoxybiphenyl
• CAS No.: 108989-36-2
• Molecular Formula: C14H12 Br2 O2
• Molecular Weight: 372.056
• Hs Code.: 2909309090
• European Community (EC) Number: 679-737-0
• DSSTox Substance ID: DTXSID90567379
• Nikkaji Number: J1.459.801D
• Wikidata: Q82453255
• Mol file: 108989-36-2.mol

Synonyms:3,3'-Dibromo-4,4'-dimethoxybiphenyl;108989-36-2;3,3-Dibromo-4,4-dimethoxybiphenyl;2-bromo-4-(3-bromo-4-methoxyphenyl)-1-methoxybenzene;3,3'-Dibromo-4,4'-dimethoxy-1,1'-biphenyl;3,3/'/'-DIBROMO-4,4/'/'-DIMETHOXYBIPHENYL;SCHEMBL12326165;DTXSID90567379;VUOOJGFHEDZGEA-UHFFFAOYSA-N;MFCD10000957;BS-50619;CS-0365804;D3603

Chemical Property of 3,3'-Dibromo-4,4'-dimethoxybiphenyl

Chemical Property:

• Melting Point: 166 °C
• PSA: 18.46000
• LogP: 4.89580
• XLogP3: 4.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 371.91836
• Heavy Atom Count: 18
• Complexity: 236

Purity/Quality:

98%,99%, ^*data from raw suppliers

3,3''-Dibromo-4,4''-dimethoxybiphenyl ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C=C(C=C1)C2=CC(=C(C=C2)OC)Br)Br

Technology Process of 3,3'-Dibromo-4,4'-dimethoxybiphenyl

There total 4 articles about 3,3'-Dibromo-4,4'-dimethoxybiphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

4,4'-Dimethoxybiphenyl (2132-80-1) → 2-bromo-4-(3-bromo-4-methoxyphenyl)-1-methoxybenzene (108989-36-2)

Guidance literature:

With N-Bromosuccinimide; In acetonitrile; for 5h; Reflux;

DOI:10.1016/j.tet.2012.10.039

Reference yield: 84.0%

4,4'-Dimethoxybiphenyl (2132-80-1) → 2-bromo-4-(3-bromo-4-methoxyphenyl)-1-methoxybenzene (108989-36-2) + 3-bromo-4,4'-dimethoxy-1,1'-biphenyl (74447-74-8)

Guidance literature:

With N-Bromosuccinimide; In acetonitrile; for 5h; Reflux;

DOI:10.1016/j.tet.2012.10.039

Reference yield: 72.0%

2-bromoanisole (578-57-4) → 2-bromo-4-(3-bromo-4-methoxyphenyl)-1-methoxybenzene (108989-36-2)

Guidance literature:

With boron trifluoride diethyl etherate; bis-[(trifluoroacetoxy)iodo]benzene; In dichloromethane; at -40 ℃; for 1.5h;

DOI:10.1016/S0040-4020(00)00941-8

upstream raw materials:

4,4'-Dimethoxybiphenyl

2-bromoanisole

Downstream raw materials:

C₂₆H₂₁BrO₂

C₃₂H₂₆O₂

C₃₂H₂₆O₂

C₂₈H₂₀F₆O₂

Refernces

• 1、 Bovicelli, Paolo,Antonioletti, Roberto,Onori, Antonella,Delogu, Giovanna,Fabbri, Davide,Dettori, Maria Antonietta. "Regioselective halogenation of biphenyls for preparation of valuable polyhydroxylated biphenyls and diquinones". . p. 635 - 639. Retrieved 2006.
• 2、 Chang, Meng-Yang,Lee, Tein-Wei,Lin, Shin-Ying. "Synthesis of polyphenyls". . p. 228 - 234. Retrieved 2013/01/15.