rac-1-monopalmitoylglycerol

Base Information

• Chemical Name: rac-1-monopalmitoylglycerol
• CAS No.: 305847-08-9
• Molecular Formula: C₁₉H₃₈O₄
• Molecular Weight: 330.508
• Mol file: 305847-08-9.mol

Synonyms:rac-1-monopalmitoylglycerol

Chemical Property of rac-1-monopalmitoylglycerol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of rac-1-monopalmitoylglycerol

There total 5 articles about rac-1-monopalmitoylglycerol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

glyceroltripalmitate (555-44-2) + glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0) → rac-1-monopalmitoylglycerol (305847-08-9) + hexadecanoic acid, 2-hydroxy-1,3-propanediyl ester (502-52-3)

Guidance literature:

With sodium methylate; at 115 ℃; for 24h;

DOI:10.1007/s11746-007-1173-y

Reference yield:

vinyl palmitate (693-38-9) + glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0) → rac-1-monopalmitoylglycerol (305847-08-9) + hexadecanoic acid, 2-hydroxy-1,3-propanediyl ester (502-52-3)

Guidance literature:

With silica gel; Lipozyme RM IM; In tert-butyl methyl ether; at 25 ℃; for 24h; Product distribution / selectivity; Enzymatic reaction;

Reference yield:

1-hexadecylcarboxylic acid (57-10-3) + glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0) → rac-1-monopalmitoylglycerol (305847-08-9) + hexadecanoic acid, 2-hydroxy-1,3-propanediyl ester (502-52-3)

Guidance literature:

With Penicillium camembertii lipase immobilized on epoxy SiO₂-PVA; at 45 - 65 ℃; Enzymatic reaction;

DOI:10.1016/j.molcatb.2009.12.009

upstream raw materials:

hexadecanoic acid methyl ester

glycerol

glyceroltripalmitate

1-hexadecylcarboxylic acid

Downstream raw materials:

1-palmitoyloxy-2,3-bis-stearoyloxy-propane

hexadecanoic acid, 2-hydroxy-1,3-propanediyl ester

1,2-dioleoyl-3-palmitoylglycerol

hexadecanoic acid 2,3-bis[(trimethylsilyl)oxy]propyl ester

Refernces

• 1、 Freitas, Larissa,Paula, Ariela V.,dos Santos, Julio C.,Zanin, Gisella M.,de Castro, Heizir F.. "Enzymatic synthesis of monoglycerides by esterification reaction using Penicillium camembertii lipase immobilized on epoxy SiO2-PVA composite". experimental part. p. 87 - 90. Retrieved 2010/10/19.
• 2、 Kharchafi, Ghizlane,Jerome, Francois,Adam, Isabelle,Pouilloux, Yannick,Barrault, Joel. "Design of well balanced hydrophilic-lipophilic catalytic surfaces for the direct and selective monoesterification of various polyols". . p. 928 - 934. Retrieved 2007/10/03.